{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T23:21:08Z","timestamp":1792452068717,"version":"4.5.0"},"reference-count":36,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Few studies have reported changes of bone mineral density (BMD) after parathyroidectomy in patients with persistent hyperparathyroidism after renal transplantation (3 HPT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>We retrospectively analyzed 14 patients who underwent successful parathyroidectomy for 3 HPT and who had available BMD data before and after parathyroidectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Median follow\u2010up time was 26\u00a0months (IQR: 16.8\u201340.2). Serum calcium levels decreased significantly after parathyroidectomy (2.32 \u00b1 0.09 versus 2.66 \u00b1 0.16\u00a0mmol\/l; <jats:italic>p<\/jats:italic> &lt; 0.01), as did PTH levels (5.1 \u00b1 3.0 versus 27.8 \u00b1 23.7 pmol\/l; <jats:italic>p<\/jats:italic> &lt; 0.01). Nine patients (64%) had a steroid\u2010free immunosuppression at follow\u2010up. Mean increase in BMD was 9.5 \u00b1 8.0% for the spine and 9.5 \u00b1 7.9% for the hip (<jats:italic>p<\/jats:italic> &lt; 0.01 for both sites). Patients with osteoporosis (T\u2010score \u2264 2.5) or osteopenia (T\u2010score \u2264 1) before parathyroidectomy had the biggest increase in BMD (10.7 \u00b1 7.7% in hip BMD and of 12.3 \u00b1 8.1% in spine BMD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Parathyroidectomy is an efficient treatment of osteoporosis and osteopenia in patients with 3 HPT.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-008-9495-y","type":"journal-article","created":{"date-parts":[[2008,3,3]],"date-time":"2008-03-03T12:45:10Z","timestamp":1204548310000},"page":"1795-1801","source":"Crossref","is-referenced-by-count":23,"title":["Increase in Bone Mineral Density after Successful Parathyroidectomy for Tertiary Hyperparathyroidism after Renal Transplantation"],"prefix":"10.1002","volume":"32","author":[{"given":"St\u00e9phane","family":"Collaud","sequence":"first","affiliation":[{"name":"Department of Thoracic and Endocrine Surgery University Hospital of Geneva Rue 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Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Binet","sequence":"additional","affiliation":[{"name":"Department of Nephrology Kantonsspital 9007 St. Gallen Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick O.","family":"Myers","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Endocrine Surgery University Hospital of Geneva Rue Micheli\u2010du\u2010Crest 24 1211 Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9","family":"Rizzoli","sequence":"additional","affiliation":[{"name":"Division of Bone Diseases University Hospital of Geneva Rue Micheli\u2010du\u2010Crest 24 1211 Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre\u2010Yves","family":"Martin","sequence":"additional","affiliation":[{"name":"Department of Nephrology University Hospital of Geneva Rue Micheli\u2010du\u2010Crest 24 1211 Geneva 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