{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T13:52:25Z","timestamp":1780321945450,"version":"3.54.1"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,3,7]],"date-time":"2008-03-07T00:00:00Z","timestamp":1204848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Parathyroidectomy for primary hyperparathyroidism (PHPT) is expected to trigger an improvement in the quality of life. This has been demonstrated previously by using the SF\u201036 questionnaire, whose interpretation is difficult in routine clinical practice. As an alternative, the 13\u2010item questionnaire developed by Pasieka et al. can be used to assess the severity of symptoms on a visual analogue from which a parathyroid assessment of symptoms score (PAS) can be calculated. The purpose of this study was to correlate results of these two assessment tools.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prospective case\u2010series study recruiting consecutive unselected patients who underwent successful parathyroidectomy for PHPT. SF\u201036(v2) and Pasieka\u2019s questionnaires were collected before parathyroidectomy and at 3, 6, and 12\u00a0months postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between November 2005 and December 2006, 101 patients were diagnosed with PHPT (30\u00a0men; aged 18\u201389 years). Preoperative PAS ranged 0\u20131040 and did not correlate with the severity of hypercalcemia (2.91 \u00b1 0.25; range, 2.56\u20133.4\u00a0mmol\/l). Scores from the SF\u201036 questionnaire were under the 50th percentile for the normal population in three domains (vitality, emotional role, and physical role). Minimally invasive parathyroidectomy was performed in 69 patients and bilateral cervical exploration in 32 patients. All were found to have a single parathyroid adenoma and were normocalcemic at 3\u201312\u00a0months after parathyroidectomy.<\/jats:p><jats:p>At follow\u2010up, there was a significant reduction of PAS from 460 \u00b1 257 preoperatively to 254 \u00b1 234 at 3\u00a0months postoperatively (<jats:italic>n<\/jats:italic> = 72), to 245 \u00b1 215 at 6\u00a0months (<jats:italic>n<\/jats:italic> = 50), and 249 \u00b1 212 at 12\u00a0months (<jats:italic>n<\/jats:italic> = 63) (<jats:italic>p<\/jats:italic> &lt; 0.05, Student\u2019s <jats:italic>t<\/jats:italic>\u2010test). There was a significant and persistent improvement in five domains of SF\u201036 questionnaire: bodily pain, general health, vitality, social functioning and mental health. Overall analysis of 244 assessments using both questionnaires demonstrated a negative correlation between increasing PAS and decreasing mental component scores and physical component scores of the SF\u201036 assessment (r<jats:sup>2<\/jats:sup> = 0.372 and 0.301, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Pasieka\u2019s parathyroid assessment of symptom scores (PAS) correlate with SF\u201036 questionnaire scores. Because PAS allows easier and faster analysis, we advocate that Pasieka\u2019s questionnaire should be integrated into the assessment of patients with PHPT as a reliable tool to identify symptomatic changes that correlate with improved quality of life.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-008-9509-9","type":"journal-article","created":{"date-parts":[[2008,3,6]],"date-time":"2008-03-06T15:16:51Z","timestamp":1204816611000},"page":"807-814","source":"Crossref","is-referenced-by-count":54,"title":["Pasieka\u2019s Parathyroid Symptoms Scores Correlate with SF\u201036 Scores in Patients Undergoing Surgery for Primary Hyperparathyroidism"],"prefix":"10.1002","volume":"32","author":[{"given":"Radu","family":"Mihai","sequence":"first","affiliation":[{"name":"Department of Endocrine Surgery, level 2 John Radcliffe Hospital Headley Way OX3 9DU Headington, Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory P.","family":"Sadler","sequence":"additional","affiliation":[{"name":"Department of Endocrine Surgery, level 2 John Radcliffe Hospital Headley Way OX3 9DU Headington, Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,3,7]]},"reference":[{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2000.110844"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.137.9.1022"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2006.12.004"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007\u20100219"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006\u20101836"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900428"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010002\u20106623\u2010y"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445\u20102197.2004.02907.x"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2007.02970.x"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010007\u20109006\u20106"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(98)70039-X"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000186337.83407.ec"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039\u20106060(03)00316\u20107"},{"issue":"2","key":"e_1_2_11_15_2","first-page":"N2","article-title":"Summary statement from a workshop on asymptomatic primary hyperparathyroidism: a perspective for the 21st century","volume":"17","author":"Bilezikian JP","year":"2002","journal-title":"J Bone Miner Res"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000120072.85692.a7"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.138.8.867"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2007.01.027"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2006.01.008"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-008-9509-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-008-9509-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-008-9509-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T15:01:32Z","timestamp":1704898892000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-008-9509-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,7]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.1007\/s00268-008-9509-9"],"URL":"https:\/\/doi.org\/10.1007\/s00268-008-9509-9","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,7]]}}}