{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:13:19Z","timestamp":1792131199698,"version":"4.4.0"},"reference-count":37,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2008,5,3]],"date-time":"2008-05-03T00:00:00Z","timestamp":1209772800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hemorrhage\u2010related mortality (HRM) associated with pelvic fractures continues to challenge trauma care. This study describes the management and outcome of hemodynamically unstable patients with a pelvic fracture, with emphasis on primary intervention for hemorrhage control and HRM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Blunt trauma patients [Injury Severity Score (ISS) \u226516] with a major pelvic fracture (Abbreviated Injury Score, pelvis \u22653) and hemodynamic instability [admission systolic blood pressure (SBP) \u226490\u00a0mmHg or receiving \u22656 units of packed red blood cells (PRBCs)\/24 hours) were included into a 48\u2010month (ending in December 2003) multicenter retrospective study of 11\u00a0major trauma centers. Data are presented as the mean \u00b1 SD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 217 patients (mean age 41 \u00b1 19 years, 71% male, ISS 42 \u00b1 16) were studied. The admission SBP was 96 \u00b1 37\u00a0mmHg and the Glascow Coma Scale (GCS) 11 \u00b1 5. Patients received 4 \u00b1 2 liters of fluids including 4 \u00b1 4 units of PRBCs in the emergency room (ER). In total, 69 (32%) patients died, among whom the HRM was 19%; 29% of the deaths were due to pelvic bleeding. Altogether, 120 of the 217 (55%) patients underwent focused abdominal sonography for trauma (FAST) or diagnostic peritoneal aspiration (DPA) and diagnostic peritoneal lavage (DPL); 60 of the 217 (28%) patients were found to have pelvic binding in the ER. In all, 53 of 109 (49%) patients had no bleeding noted at laparotomy, 26 of 106 (25%) had no abdominal findings, and 15 of 53 (28%) had had no prior abdominal investigation (FAST\/DPL\/computed tomography). Angiography was positive in 48 of 58 (83%) patients. The HRM was highest in patients with laparotomy as the primary intervention (29%) followed by the angiography group (18%), the combined laparotomy\/pelvic fixation group (16%), and the pelvic fixation\u2010only group (10%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>HRM associated with major pelvic trauma is unacceptably high especially in the laparotomy group. Hence, nontherapeutic laparotomy must be avoided, concentrating instead on arresting pelvic hemorrhage. Standards of care must be implemented and abided by.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-008-9591-z","type":"journal-article","created":{"date-parts":[[2008,5,4]],"date-time":"2008-05-04T23:25:08Z","timestamp":1209943508000},"page":"1874-1882","source":"Crossref","is-referenced-by-count":120,"title":["Acute Management of Hemodynamically Unstable Pelvic Trauma Patients: Time for a Change? 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