{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:15:23Z","timestamp":1782602123224,"version":"3.54.5"},"reference-count":20,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2008,4,23]],"date-time":"2008-04-23T00:00:00Z","timestamp":1208908800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Solitary fibrous tumor of the pleura is a rare soft\u2010tissue tumor. In search of appropriate diagnosis and treatment methods, we present our experience with 13 patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The medical charts of 13 patients treated during the last 5 years were reviewed, as well as pathological records, including immunohistochemical stains. Follow\u2010up data were obtained. In addition, a literature review with regard to treatment and clinical outcome was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our series consisted of four men and nine women with a mean age of 47 years. Two were diagnosed before operation with ultrasonography\u2010guided core needle biopsy. All patients underwent primary surgical treatment, and four of them were resected by video\u2010assisted thoracic surgery. Seven tumors were malignant and the other six were benign. Immunohistochemical staining showed nestin was positive in three malignant solitary fibrous tumors of pleura (3\/7), which were negative for CD34. Except for one, all patients were followed\u2010up for 3 to 35 (mean, 14.5) months. Among them, one patient experienced a recurrence and one patient died of brain metastasis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Ultrasonography\u2010guided core needle biopsy combined with immunohistochemical analysis might be a safe and rapid method to provide a confirmatory diagnosis before resection. For smaller, pedunculated tumors, video\u2010assisted thoracic surgery could be a powerful and useful approach. We speculate that CD34\u2010negative and nestin\u2010positive might be a malignant marker for solitary fibrous tumor of pleura.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-008-9604-y","type":"journal-article","created":{"date-parts":[[2008,4,21]],"date-time":"2008-04-21T22:09:52Z","timestamp":1208815792000},"page":"1663-1668","source":"Crossref","is-referenced-by-count":48,"title":["Solitary Fibrous Tumor of the Pleura: An Analysis of 13 Cases"],"prefix":"10.1002","volume":"32","author":[{"given":"Chunlai","family":"Lu","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery Zhongshan Hospital, Fudan University Fenglin Road 180 200032 Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Pathology Zhongshan Hospital, Fudan University 200032 Shanghai 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