{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T13:58:22Z","timestamp":1761919102595},"reference-count":27,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2008,6,10]],"date-time":"2008-06-10T00:00:00Z","timestamp":1213056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There is a lack of agreement regarding preexisting portal vein thrombosis (PVT) in patients undergoing living donor liver transplantation (LDLT). We report the results of a single\u2010center study to determine the impact of PVT on outcomes of adult LDLT recipients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Of 133 cases of adult LDLT performed between January 2000 and December 2004, a thrombectomy was performed on 22 patients (16.5%) with PVT during the transplant procedure. One hundred eleven patients without PVT (group 1) were compared with those with a thrombosis confined to the portal vein (group 2; <jats:italic>n<\/jats:italic> = 15) and patients with the thrombosis beyond the portal vein (group 3; <jats:italic>n<\/jats:italic> = 7).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The sensitivities of Doppler ultrasound and CT in detecting PVT were 50 and 63.6%. A prior history of variceal bleeding (OR = 10.6, <jats:italic>p<\/jats:italic> = 0.002) and surgical shunt surgery (OR = 28.1, <jats:italic>p<\/jats:italic> = 0.044) were found to be an independent risk factors for PVT. The rate of postoperative PVT was significantly higher in patients with PVT than in those without (18.2 vs. 2.7%; <jats:italic>p<\/jats:italic> = 0.014). In particular, the rethrombosis rate in group 3 was 28.6%. The actuarial 3\u2010year patient survival rate in PVT patients (73.6%) was similar to that of the non\u2010PVT patients (85.3%; <jats:italic>p<\/jats:italic> = 0.351). However, the actuarial 3\u2010year patient survival rate in group 3 was 38.1%, which was significantly lower than that in groups 1 and 2 (<jats:italic>p<\/jats:italic> = 0.006).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A thrombosis confined to the portal vein per se should not be considered a contraindication for LDLT.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-008-9651-4","type":"journal-article","created":{"date-parts":[[2008,6,9]],"date-time":"2008-06-09T13:48:52Z","timestamp":1213019332000},"page":"1731-1737","source":"Crossref","is-referenced-by-count":31,"title":["Thrombosis Confined to the Portal Vein Is Not a Contraindication for Living Donor Liver Transplantation"],"prefix":"10.1002","volume":"32","author":[{"given":"Jai Young","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Surgery Seoul National University College of Medicine, Seoul National University Hospital 28 Yongon\u2010dong 110\u2010744 Chongno\u2010gu, Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung\u2010Suk","family":"Suh","sequence":"additional","affiliation":[{"name":"Department of Surgery Seoul National University College of Medicine, Seoul National University Hospital 28 Yongon\u2010dong 110\u2010744 Chongno\u2010gu, Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Woo Young","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Surgery Seoul National University College of Medicine, Seoul National University Hospital 28 Yongon\u2010dong 110\u2010744 Chongno\u2010gu, Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hae Won","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery Seoul National University College of Medicine, Seoul National University Hospital 28 Yongon\u2010dong 110\u2010744 Chongno\u2010gu, Seoul 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