{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T06:34:48Z","timestamp":1775198088052,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2008,7,31]],"date-time":"2008-07-31T00:00:00Z","timestamp":1217462400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2008,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We attempted to determine population\u2010based outcomes of laparoscopic (LC) and open cholecystectomy (OC) for acute cholecystitis (AC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We used the National Hospital Discharge Surveys from 2000 through 2005. Annual medical and demographic data from a national sample of discharge records from nonfederal, short\u2010stay hospitals were queried. We identified all patients who underwent LC or OC for AC. The main outcome measures were the rate of LC or OC and in\u2010hospital morbidity and mortality. One million patients underwent cholecystectomy (859,747\u00a0LCs; 152,202 OCs) for AC during 2000\u20132005.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the cases started laparoscopically, 9.5% were converted to OC. Compared to OC, patients who underwent LC were more likely to be discharged home (91% vs. 70%), carry private insurance (47% vs. 30%), suffer less morbidity (16% vs. 36%), and have a lower unadjusted mortality (0.4% vs. 3.0%). OC was associated with a 1.3\u2010fold increase (95% confidence interval 1.1\u20131.4) in perioperative morbidity compared to LC after adjusting for patient and hospital factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Most patients in the 21st century with AC undergo LC with a low conversion rate and low morbidity. In the general population with acute cholecystitis, LC results in lower morbidity and mortality rates than OC even in the setting of open conversion.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-008-9679-5","type":"journal-article","created":{"date-parts":[[2008,7,30]],"date-time":"2008-07-30T19:27:16Z","timestamp":1217446036000},"page":"2230-2236","source":"Crossref","is-referenced-by-count":62,"title":["Current Status of Surgical Management of Acute Cholecystitis in the United States"],"prefix":"10.1002","volume":"32","author":[{"given":"Nicholas","family":"Csikesz","sequence":"first","affiliation":[{"name":"Department of Surgery, Surgical Outcomes Analysis &amp; Research University of Massachusetts Medical School 55 Lake Avenue North, S3\u2010838 01655 Worcester MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rocco","family":"Ricciardi","sequence":"additional","affiliation":[{"name":"Department of Surgery Lahey Clinic Burlington MA 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