{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T00:02:28Z","timestamp":1774051348473,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2008,9,2]],"date-time":"2008-09-02T00:00:00Z","timestamp":1220313600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2008,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Laparoscopic splenectomy (LS) is the standard procedure for normal size or moderately enlarged spleens; open splenectomy (OS) is preferred in cases of splenomegaly. In this study, indications for and complications of open and laparoscopic splenectomy were analyzed, with the aim to identify patients who will benefit from either technique.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A consecutive series of 52 patients undergoing elective open or laparoscopic splenectomy between January 2001 and December 2006 was analyzed. Spleen volume was calculated as length \u00d7 width \u00d7 depth from the pathologist\u2019s measurements.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>LS was performed in 25 patients with a median age of 41 years (range = 24\u201365). OS was performed in 27 patients with a median age of 60 years (range = 24\u201386) (<jats:italic>p<\/jats:italic> &lt; 0.001). Conversion to OS was necessary in two patients (8%). Operation time was significantly shorter in LS (<jats:italic>p<\/jats:italic> &lt; 0.05). Spleen volume was significantly greater in patients who underwent open (median = 2520\u00a0ml, range = 150\u201316,800\u00a0ml) versus laparoscopic (median = 648\u00a0ml, range = 150\u20134860\u00a0ml) splenectomy (<jats:italic>p<\/jats:italic> = 0.001). In 36% of all laparoscopic procedures, spleen volume exceeded 1000\u00a0ml. The underlying disease was mainly immunothrombocytopenia in LS patients and lymphoma and osteomyelofibrosis in OS patients. Five patients died after OS. Significantly more patients were hospitalized longer than 7\u00a0days following OS than following LS (<jats:italic>p<\/jats:italic> &lt; 0.05). Overall complication rate was higher after OS (LS, 8; OS, 13 patients; <jats:italic>p<\/jats:italic> &lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>LS was preferred in younger patients with moderate splenomegaly, while massive splenomegaly mostly led to OS. In view of the absence of technique\u2010related differences, LS can primarily be attempted in all patients.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-008-9727-1","type":"journal-article","created":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T19:12:17Z","timestamp":1220296337000},"page":"2444-2449","source":"Crossref","is-referenced-by-count":28,"title":["Laparoscopic Versus Open Splenectomy for Nontraumatic Diseases"],"prefix":"10.1002","volume":"32","author":[{"given":"Christine F.","family":"Maurus","sequence":"first","affiliation":[{"name":"Department of Visceral and Transplantation Surgery University Hospital Z\u00fcrich R\u00e4mistrasse 100 8091 Z\u00fcrich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Sch\u00e4fer","sequence":"additional","affiliation":[{"name":"Department of Visceral and Transplantation Surgery University Hospital Z\u00fcrich R\u00e4mistrasse 100 8091 Z\u00fcrich 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