{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T15:06:55Z","timestamp":1792422415265,"version":"4.5.0"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2008,10,29]],"date-time":"2008-10-29T00:00:00Z","timestamp":1225238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2009,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To treat secondary hyperparathyroidism with subtotal parathyroidectomy or total parathyroidectomy with autotransplantation might cause the disease to recur because of growth of the parathyroid remnant or the autografts. The aim of the present study was to determinate an alternative surgical treatment for secondary hyperparathyroidism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Of 94 uremic patients, 44 (median age: 50.5 years; 33 women\/11\u00a0men) were assigned to group A, patients who were not expected to receive kidney transplantation for various reasons and had total parathyroidectomy without autotransplantation; 50 (median age 46 years; 33 women\/17\u00a0men) were assigned to group B, patients who had either total parathyroidectomy with autotransplantation or subtotal total parathyroidectomy with preservation of parathyroid tissue in situ. Parameters measured included demographics, perioperative and follow\u2010up biochemistry tests, operative time, postoperative complications, length of hospital stay, patients\u2019 compliance with the postoperative calcium and 1,25 dihydroxy\u2010viatmin D supplementation regimen, symptom relief, and presence of recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean operative times were 103 and 122\u00a0min (<jats:italic>P<\/jats:italic> = 0.007); postoperative complication rates were 18.2% and 12.0% (<jats:italic>P<\/jats:italic> = 0.563); mean hospital stays were 6 and 9\u00a0days (<jats:italic>P<\/jats:italic> = 0.259); adequate patient compliance with the postoperative calcium and 1,25 dihydroxy\u2010viatmin D regimens were 84.1% and 78.0%, respectively (<jats:italic>P<\/jats:italic> = 0.6); symptom relief rates were 88.6% and 80.0% (<jats:italic>P<\/jats:italic> = 0.277). Recurrence rates over 60\u00a0months in group A and group B were 4.5% and 18.0%, resectively (<jats:italic>P<\/jats:italic> = 0.028 by Kaplan\u2010Meier analysis).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Because of the lower recurrent rate and shorter operative time, total parathyroidectomy without autotransplantation may be an option for treating patients with symptomatic secondary hyperparathyroidism who are not expected to receive kidney transplantation.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-008-9765-8","type":"journal-article","created":{"date-parts":[[2008,10,28]],"date-time":"2008-10-28T15:00:13Z","timestamp":1225206013000},"page":"248-254","source":"Crossref","is-referenced-by-count":42,"title":["Total Parathyroidectomy Without Autotransplantation for Secondary Hyperparathyroidism"],"prefix":"10.1002","volume":"33","author":[{"given":"Ming\u2010Lang","family":"Shih","sequence":"first","affiliation":[{"name":"Department of Surgery, Triservice General Hospital National Defense Medical Center 325 Cheng\u2010Kung Rd. Sec 2, Neihu, 114 Taipei Taiwan, Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan\u2010Yang","family":"Duh","sequence":"additional","affiliation":[{"name":"Department of Surgery University of California VA Medical Center, Surgical Service (112) 4150 Clemet Street 94143\u20100112 San Francisco CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung\u2010Bao","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Department of Surgery, Triservice General Hospital National Defense Medical Center 325 Cheng\u2010Kung Rd. Sec 2, Neihu, 114 Taipei Taiwan, Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih\u2010Hua","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Medicine, Triservice General Hospital National Defense Medical Center 325 Cheng\u2010Kung Rd. Sec 2, Neihu, 114 Taipei Taiwan, Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hurng\u2010Sheng","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Surgery Show\u2010Chwan Memorial Hospital 542 Chung\u2010shan Rd. Sec 1, 500 Changhua Taiwan, Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul\u2010Ling","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Medicine, Triservice General Hospital National Defense Medical Center 325 Cheng\u2010Kung Rd. Sec 2, Neihu, 114 Taipei Taiwan, Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tien\u2010Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Surgery, Triservice General Hospital National Defense Medical Center 325 Cheng\u2010Kung Rd. Sec 2, Neihu, 114 Taipei Taiwan, Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyh\u2010Cherng","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Surgery, Triservice General Hospital National Defense Medical Center 325 Cheng\u2010Kung Rd. 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