{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T17:32:30Z","timestamp":1790184750857,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,10,25]],"date-time":"2008-10-25T00:00:00Z","timestamp":1224892800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2009,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Protracted hypocalcemia is the most common complication after parathyroidectomy for secondary hyperparathyroidism. Several parameters have been identified to predict the degree of postoperative hypocalcemia. The purpose of this study was to determine whether there were any factors associated with prolonged hospitalization in these patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 81 consecutive patients with end\u2010stage renal disease and advanced secondary hyperparathyroidism who underwent parathyroidectomy between January 2004 and December 2006 were studied. The postoperative calcium infusion protocol and discharge criteria were standardized. Clinical variables were compared between patients with a shorter or longer postoperative stay.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean postoperative hospital stay was 5.6\u00a0days. Preoperative alkaline phosphatase levels were significantly higher in patients with a longer stay (<jats:italic>p<\/jats:italic> = 0.035). In a linear regression model, the postoperative length of stay was moderately but significantly correlated with preoperative alkaline phosphatase levels (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> = 0.254; <jats:italic>p<\/jats:italic> &lt; 0.001). Receiver operating characteristic analysis showed a significant area under the curve (0.678; 95% confidence interval 0.550\u20130.805; <jats:italic>p<\/jats:italic> = 0.014). With a cutoff of preoperative alkaline phosphatase levels at 200 IU\/L, the sensitivity was 0.57 and the specificity was 0.59 for predicting a prolonged stay.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A high preoperative alkaline phosphatase level is significantly associated with prolonged hospital stay in patients undergoing parathyroidectomy for secondary hyperparathyroidism.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-008-9787-2","type":"journal-article","created":{"date-parts":[[2008,10,24]],"date-time":"2008-10-24T16:05:46Z","timestamp":1224864346000},"source":"Crossref","is-referenced-by-count":37,"title":["Prolonged Hospital Stay After Parathyroidectomy for Secondary Hyperparathyroidism"],"prefix":"10.1002","volume":"33","author":[{"given":"Shih\u2010Ping","family":"Cheng","sequence":"first","affiliation":[{"name":"Department of Surgery Mackay Memorial Hospital 92, Sec 2, Chung\u2010Shan North Road 10449 Taipei Taiwan"},{"name":"Department and Institute of Pharmacology National Yang\u2010Ming University 155, Sec 2, Linong Street 11221 Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien\u2010Liang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Surgery Mackay Memorial Hospital 92, Sec 2, Chung\u2010Shan North Road 10449 Taipei Taiwan"},{"name":"Mackay Medicine, Nursing and Management College 92, Sheng\u2010Ching Road, Kwan\u2010Tu, Peitou 11260 Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han\u2010Hsiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Mackay Medicine, Nursing and Management College 92, Sheng\u2010Ching Road, Kwan\u2010Tu, Peitou 11260 Taipei Taiwan"},{"name":"Department of Nephrology Mackay Memorial Hospital 92, Sec 2, Chung\u2010Shan North Road 10449 Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie\u2010Jen","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery Mackay Memorial Hospital 92, Sec 2, Chung\u2010Shan North Road 10449 Taipei Taiwan"},{"name":"Institute of Pharmacology Taipei Medical University 250, Wu\u2010Xin Street 11031 Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsang\u2010Pai","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Surgery Mackay Memorial Hospital 92, Sec 2, Chung\u2010Shan North Road 10449 Taipei Taiwan"},{"name":"Mackay Medicine, Nursing and Management College 92, Sheng\u2010Ching Road, Kwan\u2010Tu, Peitou 11260 Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsen\u2010Long","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Surgery Mackay Memorial Hospital 92, Sec 2, Chung\u2010Shan North Road 10449 Taipei 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