{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T21:25:25Z","timestamp":1769635525982,"version":"3.49.0"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2008,12,6]],"date-time":"2008-12-06T00:00:00Z","timestamp":1228521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2009,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although laparoscopic appendectomy (LA) is widely performed in many countries, LA for complicated appendicitis, which includes perforated or gangrenous appendicitis with or without localized or disseminated peritonitis, has not become a common practice yet.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed the clinical records of 230 patients who had undergone appendectomy for complicated appendicitis: 141 had undergone LA, 84 had conventional open appendectomy (OA), and 5 patients had conversion to the open procedure after laparoscopy. The LA group (total LA) was subdivided into \u201cearly experience (early LA: cases 1\u201356)\u201d and \u201clate experience (late LA: case 57 and higher).\u201d We defined the early LA group as the comparison group to minimize selection bias.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patient demographics were similar in the early LA and OA groups (<jats:italic>P<\/jats:italic> &gt; 0.05). Wound infection was significantly more frequent in the OA group (<jats:italic>P<\/jats:italic> &lt; 0.05). Intra\u2010abdominal infection was equally common in these two groups. The overall rate of postoperative complications was significantly higher in the OA group (32.1%) than in the early LA group (18%; <jats:italic>P<\/jats:italic> &lt; 0.05). This incidence was 12.8% in the total LA group. Hospital stay was significantly shorter in the early LA group (10.6 \u00b1 3.9\u00a0days; <jats:italic>P<\/jats:italic> &lt; 0.05), and 8.9 \u00b1 3.7\u00a0days in the total LA group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings indicate that LA is safe and useful even for the treatment of complicated appendicitis if performed by an experienced surgeon.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-008-9843-y","type":"journal-article","created":{"date-parts":[[2008,12,5]],"date-time":"2008-12-05T13:40:15Z","timestamp":1228484415000},"page":"208-214","source":"Crossref","is-referenced-by-count":60,"title":["Laparoscopic Appendectomy for Complicated Appendicitis: A Comparison with Open Appendectomy"],"prefix":"10.1002","volume":"33","author":[{"given":"Goutaro","family":"Katsuno","sequence":"first","affiliation":[{"name":"Department of Surgery, Juntendo Urayasu Hospital Juntendo University 2\u20101\u20101 Tomioka 279\u20100021 Urayasu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunihiko","family":"Nagakari","sequence":"additional","affiliation":[{"name":"Department of Surgery, Juntendo Urayasu Hospital Juntendo University 2\u20101\u20101 Tomioka 279\u20100021 Urayasu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiichiro","family":"Yoshikawa","sequence":"additional","affiliation":[{"name":"Department of Surgery, Juntendo Urayasu Hospital Juntendo University 2\u20101\u20101 Tomioka 279\u20100021 Urayasu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuyoshi","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Department of Surgery, Juntendo Urayasu Hospital Juntendo University 2\u20101\u20101 Tomioka 279\u20100021 Urayasu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Fukunaga","sequence":"additional","affiliation":[{"name":"Department of Surgery, Juntendo Urayasu Hospital Juntendo University 2\u20101\u20101 Tomioka 279\u20100021 Urayasu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,12,6]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20102007\u20101021466"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1995.01430070104022"},{"key":"e_1_2_6_4_2","volume-title":"Laparoscopic versus open surgery for suspected appendicitis. 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