{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T07:27:14Z","timestamp":1792481234365,"version":"4.5.0"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T00:00:00Z","timestamp":1241654400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2009,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In the limited literature concerning abdominal wound dehiscence after laparotomy in children, reported incidences range between 0.2\u20131.2% with associated mortality rates of 8\u201345%. The goal of this retrospective case\u2010control study was to identify major risk factors for abdominal wound dehiscence in the pediatric population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients younger than aged 18 years who developed abdominal wound dehiscence in three pediatric surgical centers during the period 1985\u20132005 were identified. For each patient with abdominal wound dehiscence, four controls were selected by systematic random sampling. Patients with (a history of) open abdomen treatment or abdominal wound dehiscence were excluded as control subjects. Putative relevant patient\u2010related, operation\u2010related, and postoperative variables for both cases and control subjects were evaluated in univariate analyses and subsequently entered in multivariate stepwise logistic regression models to identify major independent predictors of abdominal wound dehiscence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total number of 63 patients with abdominal wound dehiscence and 252 control subjects were analyzed. Mean presentation of abdominal wound dehiscence was at postoperative day 5 (range, 1\u201315) and overall mortality was 11%. Hospital stay was significantly longer (<jats:italic>p<\/jats:italic> &lt; 0.001) in the case group (median, 42 vs. 10\u00a0days). Major independent risk factors for abdominal wound dehiscence were younger than aged 1 year, wound infection, median incision, and emergency surgery. Incisional hernia was reported in 12% of the patients with abdominal wound dehiscence versus 3% in the control group (<jats:italic>p<\/jats:italic> = 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Abdominal wound dehiscence is a serious complication with high morbidity and mortality. Median incisions should be avoided whenever possible.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-009-0058-7","type":"journal-article","created":{"date-parts":[[2009,5,5]],"date-time":"2009-05-05T23:33:34Z","timestamp":1241566414000},"page":"1509-1513","source":"Crossref","is-referenced-by-count":27,"title":["Risk Factors for Abdominal Wound Dehiscence in Children: A Case\u2010Control Study"],"prefix":"10.1002","volume":"33","author":[{"given":"Gabri\u00eblle H.","family":"van Ramshorst","sequence":"first","affiliation":[{"name":"Department of Surgery Erasmus University Medical Center Room Z\u2010836, P.O. Box 2040 3000 CA Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie E.","family":"Salu","sequence":"additional","affiliation":[{"name":"Department of Surgery Erasmus University Medical Center Room Z\u2010836, P.O. Box 2040 3000 CA Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaas M. A.","family":"Bax","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Erasmus University Medical Center\u2010Sophia 3000 CB RotterdamRotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wim C. J.","family":"Hop","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Erasmus University Medical Center 3000 CA Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernst","family":"van Heurn","sequence":"additional","affiliation":[{"name":"Department of Surgery Academic Hospital Maastricht 6202 AZ Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel C.","family":"Aronson","sequence":"additional","affiliation":[{"name":"Pediatric Surgical Center of Amsterdam Emma Children\u2019s Hospital AMC and Vrije Universiteit Medical Center Amsterdam The Netherlands"},{"name":"Radboud University Medical Center 6500 HB Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan F.","family":"Lange","sequence":"additional","affiliation":[{"name":"Department of Surgery Erasmus University Medical Center Room Z\u2010836, P.O. Box 2040 3000 CA Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,5,7]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010195303000\u201000007"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022\u20103468(72)90485\u2010X"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01258935"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1072\u20107515(00)00284\u20102"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00383\u2010006\u20101722\u20108"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022\u20103468(86)80016\u20101"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102141.2000.01992.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/34.suppl_A.1"},{"issue":"4","key":"e_1_2_6_10_2","first-page":"2","article-title":"Antimicrobial defenses in the neonate","volume":"14","author":"Quie PG","year":"1990","journal-title":"Semin Perinatol"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0195\u20106701(88)90206\u2010X"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1973.01350160185032"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002\u20109610(68)90495\u20109"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002\u20109610(92)90014\u2010I"},{"key":"e_1_2_6_15_2","first-page":"349","article-title":"Burst abdomen and incisional hernia after major gastrointestinal operations\u2013comparison of three closure techniques","volume":"161","author":"Gislason H","year":"1995","journal-title":"Eur J Surg"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800650722"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800710405"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800670308"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102168.2002.02258.x"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010200003000\u201000018"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-009-0058-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T23:39:32Z","timestamp":1703633972000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-009-0058-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5,7]]},"references-count":19,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2009,7]]}},"alternative-id":["10.1007\/s00268-009-0058-7"],"URL":"https:\/\/doi.org\/10.1007\/s00268-009-0058-7","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,7]]}}}