{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T13:46:18Z","timestamp":1764510378982},"reference-count":24,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2010,4,7]],"date-time":"2010-04-07T00:00:00Z","timestamp":1270598400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2010,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Intra\u2010abdominal fistulas occur in one\u2010third of patients with Crohn\u2019s disease (CD). Although they are common, these fistulas may pose difficult problems for the surgeon. We assessed the clinical presentation of intra\u2010abdominal fistulas in patients with CD and compared the clinicopathologic characteristics of CD with and without fistulas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed consecutive laparotomy cases for 254 patients with CD between 1991 and 2008. Clinicopathologic data were abstracted from patient charts and a prospectively maintained database. Patient variables with and without fistulas were analyzed using the Fisher\u2019s exact test, chi\u2010square test, and Student\u2019s <jats:italic>t<\/jats:italic> test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 93 surgical procedures were performed on 83 patients (32.7%) who had at least one intra\u2010abdominal fistula, revealing a total of 122 fistulas. Enteroenteric fistulas were the most common (30.3%), followed by enterocutaneous (23%), enterosigmoid (19.7%), enterocolonic (9.7%), and enterovesical (9.7%). Most cases (95.7%) underwent intestinal resection, with primary anastomosis in 77 of the cases (82.8%). There was no mortality, although 15 (16.1%) patients experienced postoperative complications. In the comparison of 270 cases with and without fistulas, cases with fistulas tended to have more frequent surgeries for perianal fistulas or abscesses (<jats:italic>P<\/jats:italic> = 0.001), more frequent intra\u2010abdominal abscesses on CT (<jats:italic>P<\/jats:italic> = 0.044), and a higher incidence of combined small bowel and colonic disease (<jats:italic>P<\/jats:italic> &lt; 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The incidence and clinical features of fistulas were similar to those reported in previous studies of western patients. We identified that patients with CD and fistulas have more frequent other CD\u2010related sepsis.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-010-0568-3","type":"journal-article","created":{"date-parts":[[2010,4,7]],"date-time":"2010-04-07T05:01:02Z","timestamp":1270616462000},"page":"1924-1929","source":"Crossref","is-referenced-by-count":23,"title":["Intra\u2010abdominal Fistulas in Surgically Treated Crohn\u2019s Disease Patients"],"prefix":"10.1002","volume":"34","author":[{"given":"Yong Sik","family":"Yoon","sequence":"first","affiliation":[{"name":"Department of Colon and Rectal Surgery University of Ulsan College of Medicine and Asan Medical Center 388\u20101 Pungnap\u2010dong, Songpa\u2010gu 138\u2010736 Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang Sik","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Colon and Rectal Surgery University of Ulsan College of Medicine and Asan Medical Center 388\u20101 Pungnap\u2010dong, Songpa\u2010gu 138\u2010736 Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suk\u2010Kyun","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Ulsan College of Medicine and Asan Medical Center Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Nam","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Colon and Rectal Surgery University of Ulsan College of Medicine and Asan Medical Center 388\u20101 Pungnap\u2010dong, Songpa\u2010gu 138\u2010736 Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seok\u2010Byung","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Colon and Rectal Surgery University of Ulsan College of Medicine and Asan Medical Center 388\u20101 Pungnap\u2010dong, Songpa\u2010gu 138\u2010736 Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Cheon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Colon and Rectal Surgery University of Ulsan College of Medicine and Asan Medical Center 388\u20101 Pungnap\u2010dong, Songpa\u2010gu 138\u2010736 Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,4,7]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"419","article-title":"Crohn\u2019s disease of the colon. 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