{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T08:18:41Z","timestamp":1792484321844,"version":"4.5.0"},"reference-count":13,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2010,7,16]],"date-time":"2010-07-16T00:00:00Z","timestamp":1279238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This retrospective, case\u2013control study was designed to find side effects of hypoparathyroidism after total parathyroidectomy plus autotransplantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>After successful total parathyroidectomy plus autotransplantation for symptomatic secondary hyperparathyroidism, 19 patients who had intact parathyroid hormone (iPTH) levels &lt;10 pg\/ml during the follow\u2010up period of 1 year and 38 patients, who had levels &gt;10 pg\/ml, were enrolled as the hypoparathyroid and nonhypoparathyroid groups. Data were collected on etiology, symptoms, serum levels of calcium, phosphate, alkaline phosphatase (Alk\u2010ptase), iPTH, and bone mineral density (BMD) at different sites. Then, 1 week, 3\u00a0months, and 1 year after surgery, serum levels of calcium, phosphate, Alk\u2010ptase, and iPTH were measured again. Three months later, symptoms were recorded. One year after surgery, the BMD at different sites was measured again. Patients\u2019 daily requirements of calcium carbonate and vitamin D3 were recorded at the mean follow\u2010up of 24\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Calcium, phosphate, and iPTH levels decreased significantly 1 week, 3\u00a0months, and 1 year after surgery, and Alk\u2010ptase levels increased at 1 week and then decreased significantly 3\u00a0months and 1 year after surgery. Symptoms improved significantly 3\u00a0months after surgery. The BMD of different sites increased significantly at 1 year. There were no differences between the two groups regarding changes of symptoms, BMD, and calcium, phosphate, and Alk\u2010ptase levels. Hypoparathyroid patients required significantly more calcium carbonate and vitamin D3 than nonhypoparathyroid patients did (<jats:italic>P<\/jats:italic> = 0.002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Even though hypoparathyroid patients require more calcium carbonate and vitamin D3 than nonhypoparathyroid patients do, they do not have any side effects.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-010-0711-1","type":"journal-article","created":{"date-parts":[[2010,7,15]],"date-time":"2010-07-15T11:29:03Z","timestamp":1279193343000},"page":"2350-2354","source":"Crossref","is-referenced-by-count":9,"title":["Hypoparathyroidism after Total Parathyroidectomy plus Subcutaneous Autotransplantation for Secondary Hyperparathyroidism\u2014Any Side Effects?"],"prefix":"10.1002","volume":"34","author":[{"given":"Fong\u2010Fu","family":"Chou","sequence":"first","affiliation":[{"name":"Department of Surgery, Chang Gung Memorial Hospital\u2010Kaohsiung Medical Center Chang Gung University College of Medicine 123, Ta\u2010Pei Road, Niao\u2010Sung Hsiang 833 Kaohsiung Hsien Taiwan, ROC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun\u2010Yu","family":"Chi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Chang Gung Memorial Hospital\u2010Kaohsiung Medical Center Chang Gung University College of Medicine 123, Ta\u2010Pei Road, Niao\u2010Sung Hsiang 833 Kaohsiung Hsien Taiwan, ROC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun\u2010Chou","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Department of Surgery, Chang Gung Memorial Hospital\u2010Kaohsiung Medical Center Chang Gung University College of Medicine 123, Ta\u2010Pei Road, Niao\u2010Sung Hsiang 833 Kaohsiung Hsien Taiwan, ROC"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,7,16]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(98)70067-4"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.143.8.756"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010008\u20109765\u20108"},{"key":"e_1_2_6_5_2","first-page":"70","article-title":"Long\u2010term results after surgical treatment of renal hyperparathyroidism when fever than four gland are identified at operation","volume":"184","author":"Donckier V","year":"1997","journal-title":"J Am Coll Surg"},{"key":"e_1_2_6_6_2","first-page":"5","article-title":"Combine report on regular dialysis and transplantation in Europe XX 1989","volume":"6","author":"Fassbinder W","year":"1991","journal-title":"Nephrol Dial Transplant"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01665309"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2005.03.032"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-199403000-00001"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010005\u20100379\u20100"},{"key":"e_1_2_6_11_2","first-page":"323","article-title":"Total parathyroidectomy alone or with autograft for renal hyperparathyroidism?","volume":"79","author":"Higgins RM","year":"1991","journal-title":"Q J Med"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744\u20109987.2009.00605.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.545"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2008.12.026"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-010-0711-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-010-0711-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-010-0711-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T18:38:37Z","timestamp":1703615917000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-010-0711-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7,16]]},"references-count":13,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["10.1007\/s00268-010-0711-1"],"URL":"https:\/\/doi.org\/10.1007\/s00268-010-0711-1","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,16]]}}}