{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T02:49:08Z","timestamp":1764211748845},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2010,11,19]],"date-time":"2010-11-19T00:00:00Z","timestamp":1290124800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The use of the Harmonic Scalpel (HS) for cystic duct ligation began with little data about its efficacy or safety. On the other hand, there is not any literature available about the use of PlasmaKinetic Sealer (PK) for closing the cystic duct in laparoscopic cholecystectomy (LC). Therefore, this study was designed to compare the efficacy and safety of HS and PK for achieving safe closure of the cystic ducts after LC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ninety patients with symptomatic gallstone disease were enrolled in this prospective case control study. The patients were operated with laparoscopic technic and divided into three groups (<jats:italic>n<\/jats:italic> = 30) randomly. After the dissection of Calot\u2019s triangle, proximal cystic ducts on common bile ducts were sealed with single surgical clips (SC) in all groups, and in the first group, distal of the cystic ducts also was sealed with single SC and the gallbladders were removed with SC. In the second and third groups, distal of the cystic ducts were sealed with HS and PK, respectively. The gallbladders were removed as sealed cystic ducts with HS and PK. Then, gallbladders were connected to a transducer set and increasing pressure with saline was applied. The bursting pressures of gallbladders were measured and differences between the groups were calculated by using Student\u2019s <jats:italic>t<\/jats:italic> test. The value of <jats:italic>P<\/jats:italic> &lt; 0.05 was accepted as significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In this study, the mean cystic duct bursting pressures were 332.46 \u00b1 4.62\u00a0mmHg with SC, 326.56 \u00b1 4.53\u00a0mmHg with PK, and 343.06 \u00b1 4.28\u00a0mmHg with HS. Differences of the mean cystic duct bursting pressures between the groups were indicated the superior results of HS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results of this study indicated that HS is more effective than PK and as safe and effective as SC for cystic duct closure.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-010-0819-3","type":"journal-article","created":{"date-parts":[[2010,11,18]],"date-time":"2010-11-18T16:16:15Z","timestamp":1290096975000},"page":"817-823","source":"Crossref","is-referenced-by-count":12,"title":["Clipless Cholecystectomy: Which Sealer Should be Used?"],"prefix":"10.1002","volume":"35","author":[{"given":"Burak","family":"Kavlakoglu","sequence":"first","affiliation":[{"name":"Department of General Surgery Ministry of Health, Ankara Oncology Training and Research Hospital Demetevler Ankara Turkey"},{"name":"Birlik Mah. 435. Cadde Zirvekent Zambak Sitesi No. 68\/4, Cankaya Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Recep","family":"Pekcici","sequence":"additional","affiliation":[{"name":"Department of General Surgery Ministry of Health, Ankara Training and Research Hospital Cebeci Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suleyman","family":"Oral","sequence":"additional","affiliation":[{"name":"Department of General Surgery Ministry of Health, Ankara Oncology Training and Research Hospital Demetevler Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,11,19]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2006.05.008"},{"key":"e_1_2_5_3_2","first-page":"42","article-title":"Laparoscopic cholecystectomy: an early experience at Ayub Teaching Hospital, Abbottabad","volume":"19","author":"Mufti TS","year":"2007","journal-title":"J Ayub Med Coll Abbottabad"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010004\u20102253\u20109"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s005950300003"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004649900932"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1992.01420060094014"},{"key":"e_1_2_5_8_2","first-page":"102","article-title":"Dislocation of clips of the cystic duct stump","volume":"123","author":"Geissler B","year":"1998","journal-title":"Zentralbl Chir"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002619900474"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002\u20109610(91)90596\u20106"},{"key":"e_1_2_5_11_2","first-page":"62","article-title":"Laparoscopic knot substitutes. An assessment of techniques of securing sutures through the laparoscope","volume":"2","author":"Andrews SM","year":"1994","journal-title":"Endosc Surg Allied Technol"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004649910012"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2009.236"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/000313480907501201"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004640090054"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2005.19.107"},{"key":"e_1_2_5_17_2","first-page":"283","article-title":"Clipless cholecystectomy: broadening the role of the Harmonic scalpel","volume":"8","author":"Westervelt J","year":"2004","journal-title":"J Soc Laproendosc Surg"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2005.07.029"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010002\u20109068\u20103"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2007.0227"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1308\/003588408X321558"},{"key":"e_1_2_5_22_2","first-page":"1256","article-title":"Laparoscopic cholecystectomy by harmonic dissection","volume":"13","author":"Huscher CGS","year":"1999","journal-title":"Surg Endosc"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.14.4077"},{"key":"e_1_2_5_24_2","first-page":"735","volume-title":"Gastroenterologic endoscopy","author":"Geenen JE","year":"1987"},{"key":"e_1_2_5_25_2","first-page":"130","volume-title":"Normal and disturbed motility of the gastrointestinal tract","author":"Smout AJPM","year":"1992"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440\u20101746.2009.06072.x"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800831009"},{"key":"e_1_2_5_28_2","first-page":"92","article-title":"The experimental development of an ultrasonically activated scalpel for laparoscopic use","volume":"4","author":"Amaral JF","year":"1994","journal-title":"Surg Laparosc Endosc"},{"key":"e_1_2_5_29_2","first-page":"242","article-title":"Usefulness of the ultrasonically activated scalpel in laparoscopic cholecystectomy: our experience and review of literature","volume":"29","author":"Minutolo V","year":"2008","journal-title":"G Chir"},{"key":"e_1_2_5_30_2","doi-asserted-by":"publisher","DOI":"10.3109\/13645709709153084"},{"key":"e_1_2_5_31_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004649900276"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-010-0819-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-010-0819-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-010-0819-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T15:55:03Z","timestamp":1703606103000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-010-0819-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11,19]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["10.1007\/s00268-010-0819-3"],"URL":"https:\/\/doi.org\/10.1007\/s00268-010-0819-3","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11,19]]}}}