{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T12:31:12Z","timestamp":1792413072037,"version":"4.4.0"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,10,26]],"date-time":"2010-10-26T00:00:00Z","timestamp":1288051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The purpose of the present study was to evaluate the problems, treatment outcome, and contributory factors to delayed presentation in Hirschsprung\u2019s disease (HD) after 1 year of age in a resource\u2010limited setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective study included 41 children aged &gt;1 year with HD managed at the University of Nigeria Teaching Hospital, Enugu, in south eastern Nigeria, between January 2000 and June 2009.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Complications of HD were evident at presentation in 38 (92.7%) of the 41 children. Late presentation was due to delayed referral in 27 cases (65.9%), parental ignorance in 11 (26.8%), and poverty in 3 (7.3%). The HD was rectosigmoid in 33 patients (80.5%) and was of ultra\u2010short length variety in 8 patients (19.5%). Thirty\u2010five patients (85.4%) required colostomy for decompression, and colostomy\u2010related complications occurred in 24 of them (68.6%). The definitive surgical procedure was a Swenson pullthrough in 34 cases (82.9%) and posterior myectomy in 7 others (17.1%). Twenty patients (48.8%) experienced at least one postoperative complication. After follow\u2010up of 7\u201364\u00a0months (mean: 31\u00a0months), 31 (75.6%) patients had a good outcome, 6 (14.6%) had persistent constipation, 3 had (7.3%) incontinence, and one child (2.4%) died from overwhelming infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Hirschprung\u2019s disease presenting after 1 year of age may be associated with high colostomy rates and increased morbidity. Continued dissemination of updated information on HD to medical practitioners and a public awareness campaign may improve time to diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-010-0828-2","type":"journal-article","created":{"date-parts":[[2010,10,25]],"date-time":"2010-10-25T16:37:58Z","timestamp":1288024678000},"page":"22-26","source":"Crossref","is-referenced-by-count":48,"title":["Problems and Outcome of Hirschsprung\u2019s Disease Presenting after 1 Year of Age in a Developing Country"],"prefix":"10.1002","volume":"35","author":[{"given":"S. O.","family":"Ekenze","sequence":"first","affiliation":[{"name":"Sub\u2010Department of Paediatric Surgery University of Nigeria Teaching Hospital Enugu Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Ngaikedi","sequence":"additional","affiliation":[{"name":"Sub\u2010Department of Paediatric Surgery University of Nigeria Teaching Hospital Enugu Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. A.","family":"Obasi","sequence":"additional","affiliation":[{"name":"Sub\u2010Department of Paediatric Surgery University of Nigeria Teaching Hospital Enugu Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,10,26]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20102008\u20101038625"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00383\u2010009\u20102447\u20102"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00383\u2010002\u20100842\u2010z"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022\u20103468(98)90185\u20103"},{"key":"e_1_2_6_6_2","first-page":"212","article-title":"Hirschsprung\u2019s disease in adolescents. Misadventures in diagnosis and management","volume":"55","author":"Powell RW","year":"1909","journal-title":"Am Surg"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/02724936.1982.11748220"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2009.11.017"},{"key":"e_1_2_6_9_2","first-page":"642","article-title":"Pattern of aganglionic megacolon in Calabar, Nigeria","volume":"92","author":"Archibong AE","year":"2002","journal-title":"S Afr Med J"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2007.07.017"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2004.09.052"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2007.01.008"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2003.12.016"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2006.10.049"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100029\u20101220682"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mpg.0000304448.69305.28"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-010-0828-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-010-0828-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-010-0828-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T23:15:06Z","timestamp":1704928506000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-010-0828-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,26]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["10.1007\/s00268-010-0828-2"],"URL":"https:\/\/doi.org\/10.1007\/s00268-010-0828-2","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,26]]}}}