{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T21:15:24Z","timestamp":1793222124168,"version":"4.5.0"},"reference-count":42,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This study presents our 14\u2010year surgical experience with adult choledochal cyst disease (CCD), focusing on the clinical outcomes after surgical treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records of 204 adult patients who had undergone surgery for CCD were reviewed retrospectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Median patient age was 40.2 years, and 157 (77%) of the patients were female. Todani classification was type I in 116 patients (56.9%), type II in 1 patient (0.5%), type IVa in 86 patients (42.2%), and type V in 1 patient (0.5%). Extrahepatic cyst excision and hepaticojejunostomy were performed in 185 patients (90.7%). Major perioperative complications occurred in 5 patients (2.5%), resulting in no mortality. Late complications occurred in 48 patients (23.6%). Concurrent cancer was diagnosed in 20 patients (9.8%). Mean age of patients with or without biliary cancer was 48.1 \u00b1 13.2 years and 39.1 \u00b1 11.8 years, respectively (<jats:italic>P<\/jats:italic> = 0.001). Anomalous union of the pancreaticobiliary duct was more frequently associated with gallbladder cancer than with bile duct cancer. De novo malignancy at the cyst remnant occurred in 2 patients (1%). The survival outcomes in CCD patients with concurrent biliary cancer were comparable to those in cancer patients without CCD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>As a result of diverse features of adult CCD, various clinical problems occurred after surgical excision. Surgical treatment for adult patients with CCDs having complex features should be individualized to maintain a balance between risk of surgery and potential risk of late complications.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-011-1009-7","type":"journal-article","created":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T20:56:19Z","timestamp":1299012979000},"page":"1094-1102","source":"Crossref","is-referenced-by-count":75,"title":["Surgical Experience of 204 Cases of Adult Choledochal Cyst Disease over 14 Years"],"prefix":"10.1002","volume":"35","author":[{"given":"Min\u2010Jeong","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Surgery, Asan Medical Center University of Ulsan College of Medicine 138\u2010736 Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Surgery, Asan Medical Center University of Ulsan College of Medicine 138\u2010736 Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young\u2010Joo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery, Asan Medical Center University of Ulsan College of Medicine 138\u2010736 Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki\u2010Hun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Surgery, Asan Medical Center University of Ulsan College of Medicine 138\u2010736 Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chul\u2010Soo","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Surgery, Asan Medical Center University of Ulsan College of Medicine 138\u2010736 Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deok\u2010Bog","family":"Moon","sequence":"additional","affiliation":[{"name":"Department of Surgery, Asan Medical Center University of Ulsan College of Medicine 138\u2010736 Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung\u2010Koo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Asan Medical Center University of Ulsan College of Medicine 138\u2010736 Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myung\u2010Hwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Asan Medical Center University of Ulsan College of Medicine 138\u2010736 Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang\u2010Soo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Asan Medical Center University of Ulsan College of Medicine 138\u2010736 Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Do\u2010Hyun","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Asan Medical Center University of Ulsan College of Medicine 138\u2010736 Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung\u2010Gyu","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery, Asan Medical Center University of Ulsan College of Medicine 138\u2010736 Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,3]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002\u20109610(77)90359\u20102"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002\u20109610(80)90051\u20103"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2005.01.025"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010008\u20109582\u20100"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/13651820701646198"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1155\/2009\/103739"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010199411000\u201000007"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00534\u2010002\u20100797\u20104"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2005.04.026"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2009.10.1.71"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/RCT.0b013e318064e723"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2006.09.011"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2008.08.004"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010005\u20100565\u2010z"},{"key":"e_1_2_6_16_2","first-page":"69","article-title":"Nationwide survey of cases of choledochal cyst. 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