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Following improvements in endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD), the use of LWR and IGMR for these indications decreased, and patients with gastric cancer, including those with a risk of lymph node metastases, were more likely to be managed with laparoscopic gastrectomy (LG) with lymph node dissection. Many retrospective comparative trials and randomized\u2010controlled trials (RCT) have confirmed that LG is safe and feasible, and that short\u2010term outcomes are better than those of open gastrectomy (OG) in patients with early gastric cancer (EGC). However, these trials did not include a satisfactory number of patients to establish clinical evidence. Thus, additional multicenter randomized\u2010controlled trials are needed to delineate significantly quantifiable differences between LG and OG. As laparoscopic experience has accumulated, the indications for LG have been broadened to include older and overweight patients and those with advanced gastric cancer. Moreover, advanced techniques, such as laparoscopy\u2010assisted total gastrectomy, laparoscopy\u2010assisted proximal gastrectomy, laparoscopy\u2010assisted pylorus\u2010preserving gastrectomy (PPG), and extended lymph node dissection (D2) have been widely performed.<\/jats:p><jats:p>In the near future, sentinel node navigation and robotic surgery will become additional options in minimally invasive surgery (MIS) involving LG. Such developments will improve the quality of life of patients following gastric cancer surgery.<\/jats:p>","DOI":"10.1007\/s00268-011-1051-5","type":"journal-article","created":{"date-parts":[[2011,4,8]],"date-time":"2011-04-08T05:58:35Z","timestamp":1302242315000},"page":"1469-1477","source":"Crossref","is-referenced-by-count":62,"title":["Minimally Invasive Surgery for Gastric Cancer: The Future Standard of Care"],"prefix":"10.1002","volume":"35","author":[{"given":"Keisuke","family":"Koeda","sequence":"first","affiliation":[{"name":"Department of Surgery Iwate Medical University School of Medicine 19\u20101 Uchimaru 020\u20108505 Morioka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Nishizuka","sequence":"additional","affiliation":[{"name":"Department of Surgery Iwate Medical University School of Medicine 19\u20101 Uchimaru 020\u20108505 Morioka 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