{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T03:25:43Z","timestamp":1789874743993,"version":"4.0.1"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2011,4,26]],"date-time":"2011-04-26T00:00:00Z","timestamp":1303776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Bile leakage is the most common complication after hepatectomy and its incidence is not declining. The aim of the present study was to identify predictive factors for bile leakage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Clinical data from 505 consecutive patients who underwent hepatectomy without extrahepatic bile duct resection in our department between January 2006 and December 2009 were reviewed retrospectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The incidence of bile leakage was found to be 6.7%. Multivariate analysis identified three independent factors that were significantly correlated with the occurrence of bile leakage: (1) repeat hepatectomy (<jats:italic>P<\/jats:italic> = 0.002; odds ratio [OR] 3.439; 95% confidence interval [CI] 1.552\u20137.618), (2) a cut surface area \u226557.5\u00a0cm<jats:sup>2<\/jats:sup> (<jats:italic>P<\/jats:italic> = 0.004; OR 5.296; 95% CI 1.721\u201316.302), and (3) intraoperative blood loss \u2265775\u00a0ml (<jats:italic>P<\/jats:italic> = 0.01; OR 2.808; 95% CI 1.280\u20136.160).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>More meticulous management is needed to prevent bile leakage in high\u2010risk patients.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-011-1114-7","type":"journal-article","created":{"date-parts":[[2011,4,25]],"date-time":"2011-04-25T17:50:42Z","timestamp":1303753842000},"page":"1898-1903","source":"Crossref","is-referenced-by-count":42,"title":["Predictive Factors for Bile Leakage After Hepatectomy: Analysis of 505 Consecutive Patients"],"prefix":"10.1002","volume":"35","author":[{"given":"Ryuji","family":"Yoshioka","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Surgery Cancer Institute Hospital, Japanese Foundation for Cancer Research 3\u20108\u201031 Ariake 135\u20108500 Koto\u2010ku, Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akio","family":"Saiura","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Cancer Institute Hospital, Japanese Foundation for Cancer Research 3\u20108\u201031 Ariake 135\u20108500 Koto\u2010ku, Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rintaro","family":"Koga","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Cancer Institute Hospital, Japanese Foundation for Cancer Research 3\u20108\u201031 Ariake 135\u20108500 Koto\u2010ku, Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Seki","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Cancer Institute Hospital, Japanese Foundation for Cancer Research 3\u20108\u201031 Ariake 135\u20108500 Koto\u2010ku, Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoji","family":"Kishi","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Cancer Institute Hospital, Japanese Foundation for Cancer Research 3\u20108\u201031 Ariake 135\u20108500 Koto\u2010ku, Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junji","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Hepato\u2010Biliary\u2010Pancreatic Surgery National Defense Medical College Hospital Saitama 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