{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:03:35Z","timestamp":1756382615403},"reference-count":18,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2011,4,27]],"date-time":"2011-04-27T00:00:00Z","timestamp":1303862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>While tuberculosis (TB) has been found in many parts of the body, involvement of the thyroid gland is rare. In this study we describe the clinicopathological characteristics of seven patients with primary thyroid tuberculosis (TTB).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This report is a retrospective case study of seven patients with thyroid tuberculosis who were treated surgically in our clinic between 2004 and 2010. Data collected from the cases included age, sex, clinical presentation, concurrent medical illness, initial diagnosis, and history of pulmonary tuberculosis. Testing used to establish the diagnosis of TTB included thyroid function tests, histopathological examination, a tuberculin skin test, and FNAC (fine needle aspiration cytology). Surgical procedures, antitubercular therapy, and follow\u2010up data were also analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All seven cases were females between the age of 30 and 60 years (mean = 44.1 \u00b1 9.5 years). Four cases had neck swelling and three had additional complaints of dysphagia and dyspnea. While total thyroidectomy was performed in six patients with multinodular goiter, a lobectomy was performed in one patient in whom a solitary thyroid nodule was detected. Histopathologic changes consistent with thyroid tuberculosis were detected in all patients. Thoracic X\u2010ray, erythrocyte sedimentation rate (ESR) test, and tuberculin skin test (PPD) were performed and all patients were screened for other possible foci of infection. In conclusion, all seven cases were diagnosed with primary tuberculosis. While the lobectomy patient was administered a 6\u2010month antitubercular treatment, the total\u2010thyroidectomy patients did not receive any medical treatment postoperatively. During the postoperative follow\u2010up period, which lasted between 6 and 53\u00a0months (mean = 37.3 \u00b1 18.6\u00a0months), none of the patients had a recurrence of disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Tuberculosis should be considered in the list of differential diagnoses for thyroid abscesses and nodular lesions in people living in geographic regions with a high tuberculosis prevalence.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-011-1118-3","type":"journal-article","created":{"date-parts":[[2011,4,26]],"date-time":"2011-04-26T17:33:14Z","timestamp":1303839194000},"page":"1847-1852","source":"Crossref","is-referenced-by-count":14,"title":["Thyroid Tuberculosis in Southeastern Turkey: Is This the Resurgence of a Stubborn Disease?"],"prefix":"10.1002","volume":"35","author":[{"given":"Sami","family":"Akbulut","sequence":"first","affiliation":[{"name":"Department of Surgery Diyarbakir Education and Research Hospital Op. Dr. Seref Inaloz Caddesi 21400 Diyarbakir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilgun","family":"Sogutcu","sequence":"additional","affiliation":[{"name":"Department of Pathology Diyarbakir Education and Research Hospital 21400 Diyarbakir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zulfu","family":"Arikanoglu","sequence":"additional","affiliation":[{"name":"Department of Surgery Diyarbakir Education and Research Hospital Op. Dr. Seref Inaloz Caddesi 21400 Diyarbakir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sule","family":"Bakir","sequence":"additional","affiliation":[{"name":"Department of Pathology Diyarbakir Education and Research Hospital 21400 Diyarbakir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah","family":"Ulku","sequence":"additional","affiliation":[{"name":"Department of Surgery Diyarbakir Education and Research Hospital Op. Dr. Seref Inaloz Caddesi 21400 Diyarbakir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuf","family":"Yagmur","sequence":"additional","affiliation":[{"name":"Department of Surgery Diyarbakir Education and Research Hospital Op. Dr. Seref Inaloz Caddesi 21400 Diyarbakir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,4,27]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2009.0097"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2009.0189"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010005\u20100139\u20101"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1155\/2009\/416231"},{"issue":"7","key":"e_1_2_6_6_2","first-page":"235","article-title":"Tuberculosis of the thyroid gland: magnetic resonance imaging appearances","volume":"50","author":"Madhusudhan KS","year":"2009","journal-title":"Singap Med J"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00068\u2010010\u20100040\u2010y"},{"issue":"3","key":"e_1_2_6_8_2","first-page":"27","article-title":"Overview of thyroid tuberculosis","volume":"1","author":"Muzaffar TH","year":"2008","journal-title":"Middle East J Intern Med"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2006.09.005"},{"issue":"3","key":"e_1_2_6_10_2","first-page":"65","article-title":"Tuberculosis of the thyroid gland","volume":"9","author":"Gupta KB","year":"2008","journal-title":"Pulmon"},{"issue":"2","key":"e_1_2_6_11_2","first-page":"116","article-title":"Primary tuberculosis of the thyroid gland","volume":"37","author":"Abdulsalam F","year":"2005","journal-title":"Kuwait Med J"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s005950200214"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1159\/000090244"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12070\u2010007\u20100045\u2010y"},{"issue":"1","key":"e_1_2_6_15_2","first-page":"75","article-title":"Thyroid tuberculosis","volume":"6","author":"Terzidis K","year":"2007","journal-title":"Hormones (Athens)"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1089\/105072502321085243"},{"key":"e_1_2_6_17_2","volume-title":"Goldberg's clinical tuberculosis","author":"Seed L","year":"1939"},{"key":"e_1_2_6_18_2","unstructured":"GuptaN SharmaK BarwadA SharmaM RajwanshiA DuttaP SharmaA(2010) Thyroid tuberculosis\u2014role of PCR in diagnosis of a rare entity.Cytopathology. doi:10.1111\/j.1365\u20102303.2010.00830.x"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1080\/00015458.2009.11680544"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-011-1118-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-011-1118-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-011-1118-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T05:55:10Z","timestamp":1703224510000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-011-1118-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4,27]]},"references-count":18,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["10.1007\/s00268-011-1118-3"],"URL":"https:\/\/doi.org\/10.1007\/s00268-011-1118-3","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,4,27]]}}}