{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T03:15:16Z","timestamp":1791342916398,"version":"4.3.1"},"reference-count":35,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2011,7,29]],"date-time":"2011-07-29T00:00:00Z","timestamp":1311897600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pancreatic fistula (PF) is an important factor responsible for the considerable morbidity associated with pancreaticoduodenectomy (PD). There have been many techniques proposed for the reconstruction of pancreatic digestive continuity to prevent fistula formation but which is best is still highly debated. We carried out a systematic review and meta\u2010analysis to determine the effectiveness of methods of anastomosis after PD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A full literature search was conducted in the Cochrane Controlled Trials Register Databases, Medline, and other resources irrespective of language. Randomized controlled trials (RCTs) were considered for inclusion. Analyses were carried out using RevMan software.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In all, ten RCTs that included a total of 1,408 patients were included. The meta\u2010analysis showed that the PF, postoperative complications, biliary fistula, mortality, reoperation, and length of hospital stay were not statistically different between the pancreaticogastrostomy (PG) and pancreaticojejunostomy (PJ) groups. The PF, postoperative complications, mortality, and reoperation were not statistically different between the duct\u2010to\u2010mucosa PJ and PJ groups. Binding PJ significantly decreased the PF and postoperative complications compared with conventional PJ. The PF, postoperative complications, and mortality were not statistically different between ligation of the pancreatic duct without anastomosis versus PJ.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>No pancreatic reconstruction technique after PD was found to be applicable to all kinds of pancreatic remnants in our systematic review and meta\u2010analysis. Some new approaches such as binding PJ and modified PG will be considered for study in the future.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-011-1159-7","type":"journal-article","created":{"date-parts":[[2011,7,28]],"date-time":"2011-07-28T16:19:37Z","timestamp":1311869977000},"page":"2290-2297","source":"Crossref","is-referenced-by-count":59,"title":["The Methods of Reconstruction of Pancreatic Digestive Continuity After Pancreaticoduodenectomy: A Meta\u2010Analysis of Randomized Controlled Trials"],"prefix":"10.1002","volume":"35","author":[{"given":"Sun Hu","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Hepatobiliary Surgery, Xijing Hospital Fourth Military Medical University 17 Changle Western Road 710032 Xi\u2019an Shanxi Province China"},{"name":"Department of General Surgery People\u2019s Hospital of Zhangye City Zhangye City Gansu Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke Feng","family":"Dou","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, Xijing Hospital Fourth Military Medical University 17 Changle Western Road 710032 Xi\u2019an Shanxi Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neel","family":"Sharma","sequence":"additional","affiliation":[{"name":"Core Medical Trainee Year One Lewisham Healthcare NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen Jie","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, Xijing Hospital Fourth Military Medical University 17 Changle Western Road 710032 Xi\u2019an Shanxi Province 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