{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T10:33:26Z","timestamp":1792319606259,"version":"4.4.0"},"reference-count":38,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Ischemic colitis is commonly thought to occur most often in the left hemicolon close to the splenic flexure owing to insufficient blood supply near Griffith\u2019s point. This study investigates the colorectal localization pattern, the risk factors, and the long\u2010term outcome of histologically proven ischemic colitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between 1996 and 2004, a total of 49 patients with a median age of 69 years (range 26\u201394 years) with colonoscopically assessed and histologically proven ischemic colitis were identified on behalf of the pathology database. Long\u2010term results of 43 patients were evaluated retrospectively after a median interval of 79\u00a0months (range 6\u2013163\u00a0months).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 27 patients (55%) more than one location was affected. We found 98 affected locations in 49 patients. The distribution of ischemic colitis in our group shows no significantly preferred location. In an exploratory analysis, the cecum, ascending colon, and right flexure were affected significantly more often if intake of a nonsteroidal antiinflammatory drug (NSAID) is documented. There was no association between the location of ischemic colitis and a history of smoking, peripheral artery occlusive disease, coronary heart disease, diabetes, or malignant tumor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Ischemic colitis seems not to have a predisposing site of occurrence in the colorectum, especially Griffith\u2019s point which was not afflicted significantly more often than other sites. Frequently, ischemic colitis afflicts more than one colonic location. In patients being treated with NSAIDs, ischemic colitis was observed significantly more often in the right hemicolon. Recurrence of ischemic colitis seems to be rare.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-011-1205-5","type":"journal-article","created":{"date-parts":[[2011,8,31]],"date-time":"2011-08-31T19:06:07Z","timestamp":1314817567000},"page":"2549-2554","source":"Crossref","is-referenced-by-count":30,"title":["Ischemic Colitis: Clinical Presentation, Localization in Relation to Risk Factors, and Long\u2010Term Results"],"prefix":"10.1002","volume":"35","author":[{"given":"Philippe M.","family":"Glauser","sequence":"first","affiliation":[{"name":"Department of Surgery Hospital of Liestal (affiliated with the University of Basel) 4410 Liestal Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Wermuth","sequence":"additional","affiliation":[{"name":"Department of Surgery Hospital of Liestal (affiliated with the University of Basel) 4410 Liestal 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