{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:18:42Z","timestamp":1786979922820,"version":"build-2736575974"},"reference-count":38,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2012,5,5]],"date-time":"2012-05-05T00:00:00Z","timestamp":1336176000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This prospective audit of appendicitis at a busy regional hospital reviews the spectrum and outcome of acute appendicitis in rural and peri\u2010urban South Africa.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>We conducted a prospective audit from September 2010 to September 2011 at Edendale Hospital in Pietermaritzburg, South Africa.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Over the year under review, a total of 200 patients with a provisional diagnosis of acute appendicitis were operated on at Edendale Hospital. There were 128\u00a0males (64 %) in this cohort. The mean duration of illness prior to seeking medical attention was 3.7\u00a0days. Surgical access was by a midline laparotomy in 62.5 % and by a Lanz incision in 35.5 %. Two percent of patients underwent a laparoscopic appendicectomy. The operative findings were as follows: macroscopic inflammation of the appendix without perforation in 35.5 % (71\/200) and perforation of the appendix in 57 % (114\/200). Of the perforated appendices, 44 % (51\/114) were associated with localised intra\u2010abdominal contamination and 55 % (63\/114) had generalised four\u2010quadrant soiling. Thirty percent (60\/200) required temporary abdominal closure (TAC) with planned repeat operation. Major complications included hospital\u2010acquired pneumonia in 12.5 % (25\/200), wound dehiscence in 7 % (14\/200), and renal failure in 3 % (6\/200). Postoperatively 89.5 % (179\/200) were admitted directly to the general wards, while 11 % (21\/200) required admission to the intensive care unit. The overall mortality rate was 2 % (4\/200).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The incidence of acute appendicitis amongst African patients seems to be increasing. Although it is still lower than the reported incidence amongst patients in the developed world, it is a common emergency that places a significant burden on the South African health service. The disease presents late and is associated with a high incidence of perforation which translates into significant morbidity and even mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00268-012-1626-9","type":"journal-article","created":{"date-parts":[[2012,5,4]],"date-time":"2012-05-04T10:35:14Z","timestamp":1336127714000},"page":"2068-2073","source":"Crossref","is-referenced-by-count":41,"title":["Acute Appendicitis in a Developing Country"],"prefix":"10.1002","volume":"36","author":[{"given":"Victor Y.","family":"Kong","sequence":"first","affiliation":[{"name":"Department of General Surgery Nelson R. Mandela School of Medicine, University of Kwa\u2010Zulu Natal Durban South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bojana","family":"Bulajic","sequence":"additional","affiliation":[{"name":"Department of General Surgery Nelson R. 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