{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T00:07:01Z","timestamp":1704931621950},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,11,10]],"date-time":"2012-11-10T00:00:00Z","timestamp":1352505600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>With a critical illness, intestinal complications are associated with high morbidity and mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Operative findings and outcomes of 77\u00a0intensive care unit (ICU) patients treated with colectomy are described.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three conditions led to colectomy: sepsis (S group; <jats:italic>n<\/jats:italic> = 31), fulminant <jats:italic>Clostridium difficile<\/jats:italic> colitis (Cl group; <jats:italic>n<\/jats:italic> = 25), and cardiovascular surgery (CV group; <jats:italic>n<\/jats:italic> = 21). The median Acute Physiology and Chronic Health score was &gt;25\u00a0in all groups. Thickening and distension of the colon was more frequent in the Cl group (<jats:italic>p<\/jats:italic> = 0.001), and ischemia was more frequent in the S and CV groups (<jats:italic>p<\/jats:italic> &lt; 0.001). Widespread necrosis was more frequent in the CV patients (<jats:italic>p<\/jats:italic> = 0.001). The kappa value for ischemic operative findings and histologic necrosis was 0.64 (95 % confidence interval 0.49\u20130.79). Hospital mortality was 35 % without multiple organ failure (MOF) (<jats:italic>n<\/jats:italic> = 31) and 74 % with MOF (<jats:italic>n<\/jats:italic> = 46) (<jats:italic>p<\/jats:italic> &lt; 0.001). Overall, 38 % were alive at the 1\u2010year follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Although colectomy in ICU patients is associated with high hospital mortality, patients who survive beyond their hospital stay have a good 1\u2010year outcome<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-012-1836-1","type":"journal-article","created":{"date-parts":[[2012,11,9]],"date-time":"2012-11-09T16:28:41Z","timestamp":1352478521000},"page":"333-338","source":"Crossref","is-referenced-by-count":2,"title":["Colectomy in Intensive Care Patients: Operative Findings and Outcomes"],"prefix":"10.1002","volume":"37","author":[{"given":"Seija","family":"Sipola","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, Division of Intensive Care Medicine Oulu University Hospital P.O. Box 21 90029 Oulu Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannu","family":"Syrj\u00e4l\u00e4","sequence":"additional","affiliation":[{"name":"Department of Infection Control Oulu University Hospital 90029 Oulu Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vesa","family":"Koivukangas","sequence":"additional","affiliation":[{"name":"Department of Surgery Oulu University Hospital 90029 Oulu Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jouko J.","family":"Laurila","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Division of Intensive Care Medicine Oulu University Hospital P.O. Box 21 90029 Oulu Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuomo","family":"Karttunen","sequence":"additional","affiliation":[{"name":"Department of Pathology Oulu University Hospital 90029 Oulu Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pasi","family":"Ohtonen","sequence":"additional","affiliation":[{"name":"Department of Surgery Oulu University Hospital 90029 Oulu Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juha","family":"Saarnio","sequence":"additional","affiliation":[{"name":"Department of Surgery Oulu University Hospital 90029 Oulu Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tero I.","family":"Ala\u2010Kokko","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Division of Intensive Care Medicine Oulu University Hospital P.O. 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