{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T08:16:00Z","timestamp":1785917760402,"version":"3.56.0"},"reference-count":22,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,4,10]],"date-time":"2013-04-10T00:00:00Z","timestamp":1365552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Surgical resection is often recommended in adults with intestinal intussusception (AI) because of its potential association with malignancy. We provide a contemporary algorithm for managing AI by focusing on the probability of discovering a lead point.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective study of adult patients with computed tomography (CT)\u2010confirmed intussusception who underwent operative management of AI between 1996 and 2011 at a single academic institution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010four patients were diagnosed with AI by CT scan and then managed operatively. The incidence of colonic (CI), small bowel (SBI), and retrograde intussusception (RI) was 14, 55, and 31 %, respectively. All patients with CI had a lead point, whereas none were found among patients with RI. Some 46 % of patients with SBI had a lead point. The probability of discovering a lead point in SBI was increased by past history of malignancy (RR, 3.7, <jats:italic>p<\/jats:italic> &lt; 0.001), a mass seen on preoperative CT scan (RR, 2.9, <jats:italic>p<\/jats:italic> = 0.005), and age over 60 years (RR, 2.2, <jats:italic>p<\/jats:italic> = 0.07).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A pathologic lead point is likely with CI but not with RI. Patients with SBI who are over the age of 60 years and have a history of malignancy or a mass noted on CT scan have a higher likelihood of harboring a pathologic lead point.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-013-2036-3","type":"journal-article","created":{"date-parts":[[2013,4,9]],"date-time":"2013-04-09T17:57:29Z","timestamp":1365530249000},"page":"1872-1877","source":"Crossref","is-referenced-by-count":9,"title":["Contemporary Management of Adult Intussusception: Who Needs a Resection?"],"prefix":"10.1002","volume":"37","author":[{"given":"Oliver A.","family":"Varban","sequence":"first","affiliation":[{"name":"Department of General Surgery University of Michigan Health System 2210 Taubman Center, 1500 E Medical Center Drive 48109\u20105343 Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Ardestani","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal and General Surgery Brigham and Women\u2019s Hospital 75 Francis Street 02115 Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan E.","family":"Azagury","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal and General Surgery Brigham and Women\u2019s Hospital 75 Francis Street 02115 Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bela","family":"Kis","sequence":"additional","affiliation":[{"name":"Department of Radiology Brigham and Women\u2019s Hospital 75 Francis Street 02115 Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Brooks","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal and General Surgery Brigham and Women\u2019s Hospital 75 Francis Street 02115 Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Tavakkoli","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal and General Surgery Brigham and Women\u2019s Hospital 75 Francis Street 02115 Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,4,10]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.146.3.527"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010199708000\u201000003"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00384\u2010005\u20100789\u20103"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445\u20102197.1981.tb05933.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007611\u2010197606000\u201000021"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010198102000\u201000019"},{"key":"e_1_2_6_8_2","first-page":"796","article-title":"Adult intussusception and carcinoma of the colon","volume":"147","author":"Sanders GB","year":"1958","journal-title":"Ann Surg"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2272020455"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2009.09.036"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11605\u2010011\u20101609\u20104"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/000313480707301104"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10620\u2010006\u20109163\u20108"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.08.1801"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2006.04.232"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11695\u2010008\u20109775\u20105"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2007.12.004"},{"key":"e_1_2_6_18_2","doi-asserted-by":"crossref","unstructured":"VarbanO AzaguryD ArdestaniAet al. 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