{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T18:14:50Z","timestamp":1780856090749,"version":"3.54.1"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,12,31]],"date-time":"2013-12-31T00:00:00Z","timestamp":1388448000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The incidence of chronic kidney disease (CKD) is increasing, which might be an obstacle to various aspects of gastric cancer treatment, such as perisurgical management and postsurgical follow\u2010up. The present study aimed to evaluate the short\u2010 and long\u2010term surgical outcomes following gastrectomy in patients with CKD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed surgical complications and prognosis of patients with gastric cancer. These patients were divided into three groups according to the glomerular filtration rate (GFR): 49 patients with severe CKD (GFR &lt; 29\u00a0ml\/min\/1.73\u00a0m<jats:sup>2<\/jats:sup>), 128 with mild CKD (GFR 30\u201359), and 798\u00a0in the controls (GFR \u2265 60).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The incidences of anastomotic leakage and intraabdominal abscess in the mild and severe CKD groups were higher than that in the control group. The incidences of wound infection, cardiovascular and pulmonary events, and in\u2010hospital mortality in the severe CKD group were higher than those in the other two groups. Severe surgical complications were associated with co\u2010morbidities other than CKD, serum albumin level, estimated blood loss, surgery duration in the mild and severe CKD group. The 3\u2010year overall survival rates for the severe CKD, mild CKD, and control groups were 48.6, 80.9, and 85.0 %, respectively, indicating significant differences between the severe CKD group and other two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients with severe CKD show an increased risk of morbidity and mortality following gastrectomy, and their prognosis is usually poor. Studies with a large cohort are essential to refine the risk stratification for gastrectomy in this high\u2010risk population.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-013-2436-4","type":"journal-article","created":{"date-parts":[[2013,12,30]],"date-time":"2013-12-30T15:38:50Z","timestamp":1388417930000},"page":"1453-1460","source":"Crossref","is-referenced-by-count":28,"title":["Short\u2010Term and Long\u2010Term Outcomes After Gastrectomy for Gastric Cancer in Patients With Chronic Kidney Disease"],"prefix":"10.1002","volume":"38","author":[{"given":"Sohei","family":"Matsumoto","sequence":"first","affiliation":[{"name":"Department of Surgery Nara Medical University School of Medicine 840 Shijo\u2010cho 634\u20108522 Kashihara Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyoshi","family":"Takayama","sequence":"additional","affiliation":[{"name":"Department of Surgery Nara Medical University School of Medicine 840 Shijo\u2010cho 634\u20108522 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