{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T13:45:42Z","timestamp":1784036742176,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,1,10]],"date-time":"2014-01-10T00:00:00Z","timestamp":1389312000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although various complications after hepatectomy have been reported, there have been no large studies on postoperative portal vein thrombosis (PVT) as a complication. This study evaluated the incidence, risk factors, and clinical outcomes of PVT after hepatectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The preoperative and postoperative clinical characteristics of patients who underwent hepatectomy were retrospectively analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 208 patients were reviewed. The incidence of PVT after hepatectomy was 9.1 % (<jats:italic>n<\/jats:italic> = 19), including main portal vein (MPV) thrombosis (<jats:italic>n<\/jats:italic> = 7) and peripheral portal vein (PPV) thrombosis (<jats:italic>n<\/jats:italic> = 12). Patients with MPV thrombosis had a significantly higher incidence of right hepatectomy (<jats:italic>p<\/jats:italic> &lt; 0.001), larger resection volume (<jats:italic>p<\/jats:italic> = 0.003), and longer operation time (<jats:italic>p<\/jats:italic> = 0.021) than patients without PVT (<jats:italic>n<\/jats:italic> = 189). Multivariate analysis identified right hepatectomy as a significant independent risk factor for MPV thrombosis (odds ratio 108.9; <jats:italic>p<\/jats:italic> &lt; 0.001). Patients with PPV thrombosis had a significantly longer duration of Pringle maneuver than patients without PVT (<jats:italic>p<\/jats:italic> = 0.002). Among patients who underwent right hepatectomy, those with PVT (<jats:italic>n<\/jats:italic> = 6) had a significantly lower early liver regeneration rate than those without PVT (<jats:italic>n<\/jats:italic> = 13; <jats:italic>p<\/jats:italic> = 0.040), and those with PVT had deterioration of liver function on postoperative day 7. In all patients with MPV thrombosis who received anticoagulation therapy, PVT subsequently resolved.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Postoperative PVT after hepatectomy is not rare. It is closely related to delayed recovery of liver function and delayed liver regeneration.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-013-2440-8","type":"journal-article","created":{"date-parts":[[2014,1,9]],"date-time":"2014-01-09T17:35:31Z","timestamp":1389288931000},"page":"1491-1497","source":"Crossref","is-referenced-by-count":56,"title":["Portal Vein Thrombosis After Hepatectomy"],"prefix":"10.1002","volume":"38","author":[{"given":"Shohei","family":"Yoshiya","sequence":"first","affiliation":[{"name":"Department of Surgery and Science, Graduate School of Medical Sciences Kyushu University 3\u20101\u20101 Maidashi, Higashi\u2010ku 812\u20108582 Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Shirabe","sequence":"additional","affiliation":[{"name":"Department of Surgery and Science, Graduate School of Medical Sciences Kyushu University 3\u20101\u20101 Maidashi, Higashi\u2010ku 812\u20108582 Fukuoka 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