{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T21:21:20Z","timestamp":1779916880709,"version":"3.53.1"},"reference-count":15,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2014,4,14]],"date-time":"2014-04-14T00:00:00Z","timestamp":1397433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2014,4,14]],"date-time":"2014-04-14T00:00:00Z","timestamp":1397433600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>\nHypoparathyroidism is the most common complication after thyroidectomy and the main reason for frequent outpatient visits; however, there is a poor understanding of its outcomes and no clear follow\u2010up strategies are available. We aimed to predict post\u2010thyroidectomy hypoparathyroidism outcomes and identify relevant factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A multicenter, standardized prospective study was conducted. The parathyroid hormone level (PTH) was measured preoperatively and at the first hour after surgery, then at each outpatient follow\u2010up visit after 1 week, 3 weeks, and 1\u00a0month, and then every 2\u00a0months, until it either reached normal values or up to 6\u00a0months. Cox proportional hazard modeling was used to determine the factors that affect PTH recovery. A Weibull distribution model was used to predict time to recovery. Both models were evaluated by goodness of fit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 186 patients were enrolled in the study; 53 (28.5 %) developed hypoparathyroidism, 47 of them (88.6 %) females. Their mean age was 41.2 years, and 11.4 % were diabetic. Of these women, 33 (62.3 %) recovered within 1\u00a0month, 10 (18.9 %) recovered after 1\u00a0month but within 6\u00a0months, 7 (13.2 %) did not recover within 6\u00a0months, and 3 (5.6 %) missed follow\u2010up. Factors that are found to affect and predict the speed of recovery were the preoperative PTH level, perioperative percent drop in PTH level, diabetes mellitus, and gender.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study provides potentially useful information for early prediction of PTH recovery, and it highlights the factors that affect the course of hypoparathyroidism recovery, which in turn should be reflected in better patient management, improved patient satisfaction, and overall cost\u2010effectiveness.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-014-2571-6","type":"journal-article","created":{"date-parts":[[2014,4,13]],"date-time":"2014-04-13T18:28:42Z","timestamp":1397413722000},"page":"2304-2310","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Factors Predicting Post\u2010thyroidectomy Hypoparathyroidism Recovery"],"prefix":"10.1002","volume":"38","author":[{"given":"Saleh F.","family":"Al\u2010Dhahri","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery King Fahad Medical City Riyadh Saudi Arabia"},{"name":"Department of Otolaryngology, Head and Neck Surgery King Saud University Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Mubasher","sequence":"additional","affiliation":[{"name":"Department of Clinical Research &amp; Biostatistics King Fahad Medical City Riyadh Saudi Arabia"},{"name":"University of Texas Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khamis","family":"Mufarji","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery King Fahad Medical City Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osama S.","family":"Allam","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery King Saud University Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah S.","family":"Terkawi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology King Fahad Medical City Riyadh Saudi Arabia"},{"name":"Department of Anesthesiology University of Virginia Charlottesville VA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,4,14]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.128.4.389"},{"key":"e_1_2_6_3_2","first-page":"342","article-title":"Accuracy of postthyroidectomy parathyroid hormone and corrected calcium levels as early predictors of clinical hypocalcemia","volume":"39","author":"Fahad Al\u2010Dhahri S","year":"2010","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1308\/003588409X359349"},{"key":"e_1_2_6_5_2","first-page":"501","article-title":"Hypoparathyroidism after surgery on thyroid cancer: is there a delayed chance for recovery after a prolonged period of substitutive therapy?","volume":"57","author":"Jurecka\u2010Lubieniecka B","year":"2006","journal-title":"Endokrynol Pol"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900459"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7219"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2010.03.059"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2010.05.007"},{"key":"e_1_2_6_10_2","unstructured":"SmithT SmithB(2013)Survival analysis and the application of Cox\u2019s proportional hazards modeling using SAS 244\u201026.http:\/\/www2.sas.com\/proceedings\/sugi26\/p244\u201026.pdf. 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