{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T15:59:32Z","timestamp":1790783972587,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T00:00:00Z","timestamp":1412294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T00:00:00Z","timestamp":1412294400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To evaluate the evidence comparing systematic mediastinal lymphadenectomy (SML) and mediastinal lymph node sampling (MLS) in the treatment of pathological stage I NSCLC using meta\u2010analytical techniques.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A literature search was undertaken until January 2014 to identify the comparative studies evaluating 1\u2010, 3\u2010, and 5\u2010year survival rates. The pooled odds ratios (OR) and the 95 % confidence intervals (95 % CI) were calculated with either the fixed or random effect models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One RCT study and four retrospective studies were included in our meta\u2010analysis. These studies included a total of 711 patients: 317 treated with SML, and 394 treated with MLS. The SML and the MLS did not demonstrate a significant difference in the 1\u2010year survival rate. There were significant statistical differences between the 3\u2010year (<jats:italic>P<\/jats:italic> = 0.03) and 5\u2010year survival rates (<jats:italic>P<\/jats:italic> = 0.004), which favored SML.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This meta\u2010analysis suggests that in pathological stage I NSCLC, the MLS can get the similar outcome to the SML in terms of 1\u2010year survival rate. However, the SML is superior to MLS in terms of 3\u2010 and 5\u2010year survival rates.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-014-2804-8","type":"journal-article","created":{"date-parts":[[2014,10,2]],"date-time":"2014-10-02T13:45:36Z","timestamp":1412257536000},"page":"410-416","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Systematic Mediastinal Lymphadenectomy or Mediastinal Lymph Node Sampling in Patients With Pathological Stage I NSCLC: A Meta\u2010Analysis"],"prefix":"10.1002","volume":"39","author":[{"given":"Siyuan","family":"Dong","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery First Hospital of China Medical University Shenyang Liaoning People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery First Hospital of China Medical 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