{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T17:33:52Z","timestamp":1749058432648},"reference-count":42,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,10,22]],"date-time":"2014-10-22T00:00:00Z","timestamp":1413936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2014,10,22]],"date-time":"2014-10-22T00:00:00Z","timestamp":1413936000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of the present study was to clarify both short\u2010term and long\u2010term results of patients with concomitant hepatocellular carcinoma (HCC) and high\u2010risk oesophagogastric varices (OGV).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective study identified 927 cirrhotic patients who underwent curative resection of HCC between 1995 and 2012\u00a0in single institution. Patients were separated into 3\u00a0groups (A, B, and C) according to general rules for recording endoscopic findings of oesophagogastric varices proposed in Japan in 1991. Groups A, B, and C consisted of patients without OGV (F0), patients with mild to moderate OGV (F1 to F2), and patients with high\u2010risk OGV (F3 and\/or red color sign), respectively. All patients in group C underwent prophylactic endoscopic variceal ligation\/sclerotherapy. Post\u2010operative complications, mortality, overall survival, and disease\u2010free survival were compared among 3\u00a0groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No patient had post\u2010operative variceal bleeding. Complication rates of Clavien\u2010Dindo grade II to V in three groups were 13.6, 14.0, and 6.9 %, respectively (<jats:italic>P<\/jats:italic> &gt; 0.05). Operative mortality, 5\u2010year overall survival rate, and disease\u2010free survival rate among the 3\u00a0groups were not significantly different (<jats:italic>P<\/jats:italic> &gt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Prophylactic endoscopic variceal ligation\/sclerotherapy effectively prevented from post\u2010operative variceal bleeding in patients with high\u2010risk OGV. Operative mortality, major morbidity, and survival of patients with high\u2010risk OGV were similar to those of patients without OGV or those with mild OGV. Liver resection remains a feasible choice for cirrhotic patients with concomitant HCC and high\u2010risk OGV.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-014-2811-9","type":"journal-article","created":{"date-parts":[[2014,10,22]],"date-time":"2014-10-22T03:40:25Z","timestamp":1413949225000},"page":"461-468","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Impact of Severe Oesophagogastric Varices on Liver Resection for Hepatocellular Carcinoma in Cirrhotic Patients"],"prefix":"10.1002","volume":"39","author":[{"given":"Hsiao\u2010Tien","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Surgery Taichung Veterans General Hospital 1650 Taiwan Boulevard Sect.\u00a04 40705 Taichung Taiwan, Roc"},{"name":"Department of Surgery Chung\u2010Shan Medical University Taichung Taiwan, 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