{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:07:29Z","timestamp":1791486449410,"version":"4.3.4"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,12,2]],"date-time":"2014-12-02T00:00:00Z","timestamp":1417478400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2014,12,2]],"date-time":"2014-12-02T00:00:00Z","timestamp":1417478400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We sought to validate the feasibility of preserving a functioning recurrent laryngeal nerve (RLN) invaded by papillary thyroid carcinoma (PTC) using a shaving technique followed by high\u2010dose radioactive iodine (RAI) therapy.\n<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review of 34 patients with locally invasive PTC who had exclusive tumor involvement of a functioning RLN was performed. All patients underwent total thyroidectomy and high\u2010dose RAI therapy. A shaving technique was conducted with the goal of leaving the smallest amount of residual tumor as possible while attempting to preserve nerve function. Clinicopathologic factors and oncologic outcomes of the patients with resected RLN (group A, <jats:italic>n<\/jats:italic> = 14) and preserved RLN (group B, <jats:italic>n<\/jats:italic> = 20) were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The two groups showed no differences in clinicopathologic factors or follow\u2010up period. Mean dose of radioiodine therapy was 245.0 \u00b1 140.3\u00a0mCi (range 100\u2013540\u00a0mCi). Permanent postoperative vocal cord paralysis after RLN shaving occurred in two patients of group B (10 %). Only one patient (5 %) in group B had local recurrence at the thyroid bed where the residual tumor was located. The overall recurrence rate was 35.7 % (5\/14) and 20.0 % (4\/20) in groups A and B, respectively showing no significant difference (<jats:italic>p<\/jats:italic> = 0.525). There were no cases of death due to PTC during the median follow\u2010up of 75\u00a0months (range 36\u2013159\u00a0months).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients with locally invasive PTC with exclusive involvement of a functioning RLN may be treated by nerve shaving followed by treatment of the macroscopic residual tumor with high\u2010dose RAI therapy.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-014-2906-3","type":"journal-article","created":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T19:33:37Z","timestamp":1417462417000},"page":"969-974","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Papillary Thyroid Carcinoma with Exclusive Involvement of a Functioning Recurrent Laryngeal Nerve May Be Treated with Shaving Technique"],"prefix":"10.1002","volume":"39","author":[{"given":"Hyoung Shin","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery, Kosin University Gospel Hospital Kosin University College of Medicine Am\u2010Nam Dong 34, Seo\u2010Gu 602\u2010702 Busan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Won","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery, Kosin University Gospel Hospital Kosin University College of Medicine Am\u2010Nam Dong 34, Seo\u2010Gu 602\u2010702 Busan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taejung","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery, Kosin University Gospel Hospital Kosin University College of Medicine Am\u2010Nam Dong 34, Seo\u2010Gu 602\u2010702 Busan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gi Yun","family":"Nam","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery, Kosin University Gospel Hospital Kosin University College of Medicine Am\u2010Nam Dong 34, Seo\u2010Gu 602\u2010702 Busan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong Chul","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Dong\u2010A University College of Medicine Busan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang Dae","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery, Kosin University Gospel Hospital Kosin University College of Medicine Am\u2010Nam Dong 34, Seo\u2010Gu 602\u2010702 Busan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,12,2]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.18.2164"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23619"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.MLG.0000200428.26975.86"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010004\u20107419\u2010z"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2880160211"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0194\u20105998(95)70143\u20105"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010199707000\u201000012"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010013\u20102984\u20108"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010005\u20100270\u2010z"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/107327481101800203"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2013.06.052"}],"container-title":["World 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