{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:58:25Z","timestamp":1791979105035,"version":"4.4.0"},"reference-count":9,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,2,24]],"date-time":"2015-02-24T00:00:00Z","timestamp":1424736000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,2,24]],"date-time":"2015-02-24T00:00:00Z","timestamp":1424736000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Management of malignant pericardial effusion (PE) is complex. Cardiac surgeons are not necessarily familiar with or are challenged by the many underlying etiologies. Analyzing risk factors for mortality may help to estimate the benefit of surgery in high\u2010risk patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients undergoing a surgical pericardiotomy for malignant PE, between 2001 and 2011, were included. The influence of tumor type, disease extension, intra\u2010pericardial tumor infiltration on early mortality and long\u2010term survival as well as freedom from symptoms after drainage, and the use of sclerosing agents on PE recurrence rates was analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>PE drainage was performed on 46 patients 12 \u00b1 30\u00a0months after tumor diagnosis. Malignant diseases were lung cancers (50 %), breast cancers (15 %), lymphoma and leukemia (13 %), cancers of the digestive tract (13 %), and others (9 %). 80 % of patients were symptomatic and symptom relief was achieved in 65 %. Nobody died during surgery. Recurrence rate was 4 %. Early in\u2010hospital mortality was 22 %. After 1 year, 29 % of patients were alive. Eleven patients (24 %) had a complete tumor regression. Metastatic spread (<jats:italic>p<\/jats:italic> &lt; 0.001), pericardial infiltration (<jats:italic>p<\/jats:italic> = 0.02), and intra\u2010pericardial Bleomycin (<jats:italic>p<\/jats:italic> = 0.01) injection were associated with increased mortality. Hematological malignancies had a better prognosis for survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Surgical pericardiotomy is safe, associated with a low recurrence rate and symptom relief in the majority of dyspneic patients. Intra\u2010pericardial Bleomycin may reduce recurrent effusion but does not ameliorate survival. Long\u2010term survival rate was low with an increased mortality in cases of metastatic spreading, pericardial infiltration, and as the tumor of origin: breast cancers. Leukemic and lymphatic tumors have better prognosis.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-015-3025-5","type":"journal-article","created":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T19:35:21Z","timestamp":1424720121000},"page":"1767-1772","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Survival After Surgical Drainage of Malignant Pericardial Effusion"],"prefix":"10.1002","volume":"39","author":[{"given":"Lars","family":"Niclauss","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery University Hospital of Lausanne 46, rue du Bugnon 1011 Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Montemurro","sequence":"additional","affiliation":[{"name":"Ospedale Bellinzona Oncology Institute of Southern Switzerland Bellinzona Switzerland"},{"name":"Department of Oncology University Hospital of Lausanne Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9","family":"Pr\u00eatre","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery University Hospital of Lausanne 46, rue du Bugnon 1011 Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,2,24]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2004.02.002"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2013.05.066"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6604866"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.4330\/wjc.v3.i5.135"},{"key":"e_1_2_5_6_2","first-page":"5111","article-title":"Cytological features of lung adenocarcinoma with micropapillary pattern in the pleural or pericardial effusion: analysis of 5 cases","volume":"7","author":"Ishida M","year":"2014","journal-title":"Int J Clin Exp Pathol"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.4330\/wjc.v2.i9.270"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.21246"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/106.1.29"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.5.1412"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-015-3025-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-015-3025-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-015-3025-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T23:44:05Z","timestamp":1703634245000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-015-3025-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,24]]},"references-count":9,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["10.1007\/s00268-015-3025-5"],"URL":"https:\/\/doi.org\/10.1007\/s00268-015-3025-5","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,24]]}}}