{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:15:32Z","timestamp":1791195332080,"version":"4.1.0"},"reference-count":49,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,8,19]],"date-time":"2016-08-19T00:00:00Z","timestamp":1471564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2016,8,19]],"date-time":"2016-08-19T00:00:00Z","timestamp":1471564800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2016,8,19]],"date-time":"2016-08-19T00:00:00Z","timestamp":1471564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"St.Olavs Hospital, Trondheim University Hospital"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Open abdomen treatment (OAT) is a significant burden for patients and is associated with considerable mortality. The primary aim of this study was to report survival and cause of mortality after OAT. Secondary aims were to evaluate length of stay (LOS) in intensive care unit (ICU) and in hospital, time to abdominal closure and major complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective review of prospectively registered patients undergoing OAT between October 2006 and June 2014 at Trondheim University Hospital, Norway.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 118 patients with OAT had a median age of 63 (20\u201388) years. OAT indications were abdominal compartment syndrome (ACS) (<jats:italic>n<\/jats:italic> = 53), prophylactic (<jats:italic>n<\/jats:italic> = 29), abdominal contamination\/second look laparotomy (<jats:italic>n<\/jats:italic> = 22), necrotizing fasciitis (<jats:italic>n<\/jats:italic> = 7), hemorrhage packing (<jats:italic>n<\/jats:italic> = 4) and full\u2010thickness wound dehiscence (<jats:italic>n<\/jats:italic> = 3). Eight percent were trauma patients. Vacuum\u2010assisted wound closure (VAWC) with mesh\u2010mediated traction (VAWCM) was used in 92 (78 %) patients, the remaining 26 (22 %) had VAWC only. Per\u2010protocol primary fascial closure rate was 84 %. Median time to abdominal closure was 12\u00a0days (1\u2013143). LOS in the ICU was 15 (1\u201389), and in hospital 29 (1\u2013246) days. Eighty\u2010one (68 %) patients survived the hospital stay. Renal failure requiring renal replacement therapy (RRT) (OR 3.9, 95 % CI 1.37\u201311.11), ACS (OR 3.1, 95 % CI 1.19\u20138.29) and advanced age (OR 1.045, 95 % CI 1.004\u20131.088) were independent predictors of mortality in multivariate analysis. The nine patients with an entero\u2010atmospheric fistula (EAF) survived.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Two\u2010thirds of the patients treated with OAT survived. Renal failure with RRT, ACS and advanced age were predictors of mortality, whereas EAF was not associated with increased mortality.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-016-3694-8","type":"journal-article","created":{"date-parts":[[2016,8,19]],"date-time":"2016-08-19T13:48:10Z","timestamp":1471614490000},"page":"152-161","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Open Abdomen Treated with Negative Pressure Wound Therapy: Indications, Management and Survival"],"prefix":"10.1002","volume":"41","author":[{"given":"A.","family":"Seternes","sequence":"first","affiliation":[{"name":"Departments of Vascular Surgery, St. Olavs Hospital Trondheim University Hospital Prinsesse Kristinas gate 3 7006 Trondheim Norway"},{"name":"Departments of Cancer Research and Molecular Medicine Norwegian University of Science and Technology (NTNU) H\u00f8gskoleringen 1 7491 Trondheim Norway"},{"name":"Departments of Circulation and Medical Imaging Norwegian University of Science and Technology (NTNU) 7006 Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. C.","family":"Rekstad","sequence":"additional","affiliation":[{"name":"Departments of Gastrointestinal Surgery, St. Olavs Hospital Trondheim University Hospital Prinsesse Kristinas gate 3 7006 Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Mo","sequence":"additional","affiliation":[{"name":"Departments of Anesthesiology and Intensive Care Medicine, St. Olavs Hospital Trondheim University Hospital Prinsesse Kristinas gate 3 7006 Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Klepstad","sequence":"additional","affiliation":[{"name":"Departments of Anesthesiology and Intensive Care Medicine, St. Olavs Hospital Trondheim University Hospital Prinsesse Kristinas gate 3 7006 Trondheim Norway"},{"name":"Departments of Circulation and Medical Imaging Norwegian University of Science and Technology (NTNU) 7006 Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. L.","family":"Halvorsen","sequence":"additional","affiliation":[{"name":"Departments of Urologic Surgery, St. Olavs Hospital Trondheim University Hospital Prinsesse Kristinas gate 3 7006 Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Dahl","sequence":"additional","affiliation":[{"name":"Departments of Vascular Surgery, St. Olavs Hospital Trondheim University Hospital Prinsesse Kristinas gate 3 7006 Trondheim Norway"},{"name":"Departments of Circulation and Medical Imaging Norwegian University of Science and Technology (NTNU) 7006 Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bj\u00f6rck","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, Section of Vascular Surgery Uppsala University 751 85 Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Wibe","sequence":"additional","affiliation":[{"name":"Departments of Gastrointestinal Surgery, St. Olavs Hospital Trondheim University Hospital Prinsesse Kristinas gate 3 7006 Trondheim Norway"},{"name":"Departments of Cancer Research and Molecular Medicine Norwegian University of Science and Technology (NTNU) H\u00f8gskoleringen 1 7491 Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,19]]},"reference":[{"issue":"1190","key":"e_1_2_7_2_2","first-page":"6","article-title":"Intra\u2010abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome","volume":"39","author":"Kirkpatrick AW","year":"2013","journal-title":"Intensive Care Med"},{"issue":"591","key":"e_1_2_7_3_2","first-page":"6","article-title":"Prospective study of the incidence and outcome of intra\u2010abdominal hypertension and the abdominal compartment syndrome","volume":"89","author":"Hong JJ","year":"2002","journal-title":"Br J Surg"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2011.02.021"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.12.030"},{"issue":"1","key":"e_1_2_7_6_2","first-page":"S62","article-title":"Intra\u2010abdominal hypertension and abdominal compartment syndrome in nontrauma surgical patients","volume":"77","author":"Bj\u00f6rck M","year":"2011","journal-title":"Am Surg"},{"issue":"588","key":"e_1_2_7_7_2","first-page":"4","article-title":"Open abdomen treatment after aortic aneurysm repair with vacuum\u2010assisted wound closure and mesh\u2010mediated fascial traction","volume":"45","author":"S\u00f6relius K","year":"2013","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31817c7a4d"},{"issue":"315","key":"e_1_2_7_9_2","first-page":"2","article-title":"Incidence and prognosis of intraabdominal hypertension in a mixed population of critically ill patients: a multiple\u2010center epidemiological study","volume":"33","author":"Malbrain ML","year":"2005","journal-title":"Crit Care Med"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/cc4870"},{"key":"e_1_2_7_11_2","unstructured":"De WaeleJJ KimballE MalbrainM et al. (2016) Decompressive laparotomy for abdominal compartment syndrome.Br J Surg"},{"issue":"804","key":"e_1_2_7_12_2","first-page":"7","article-title":"Outcomes in surgical versus medical patients with the secondary abdominal compartment syndrome","volume":"194","author":"Cothren CC","year":"2007","journal-title":"Am J Surg"},{"issue":"764","key":"e_1_2_7_13_2","first-page":"9","article-title":"Surgical decompression for abdominal compartment syndrome in severe acute pancreatitis","volume":"145","author":"Mentula P","year":"2010","journal-title":"Arch Surg"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2014.01.007"},{"issue":"238","key":"e_1_2_7_15_2","first-page":"2","article-title":"One hundred percent fascial approximation with sequential abdominal closure of the open abdomen","volume":"192","author":"Cothren CC","year":"2006","journal-title":"Am J Surg"},{"issue":"586","key":"e_1_2_7_16_2","first-page":"2","article-title":"Prospective evaluation of vacuum\u2010assisted closure in abdominal compartment syndrome and severe abdominal sepsis","volume":"205","author":"Perez D","year":"2007","journal-title":"J Am Coll Surg"},{"issue":"89","key":"e_1_2_7_17_2","first-page":"5","article-title":"Preventing loss of domain: a management strategy for closure of the \u201copen abdomen\u201d during the initial hospitalization","volume":"66","author":"Koss W","year":"2009","journal-title":"J Surg Educ"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01664876"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800730514"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005373\u2010199602000\u201000014"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005373\u2010199006000\u201000011"},{"issue":"30","key":"e_1_2_7_22_2","first-page":"5","article-title":"Temporary closure of open abdominal wounds: the vacuum pack","volume":"61","author":"Brock WB","year":"1995","journal-title":"Am Surg"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12281"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010007\u20109222\u20100"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e31817fa451"},{"issue":"947","key":"e_1_2_7_26_2","first-page":"3","article-title":"Vacuum\u2010assisted closure in severe abdominal sepsis with or without retention sutured sequential fascial closure: a clinical trial","volume":"148","author":"Pliakos I","year":"2010","journal-title":"Surgery"},{"key":"e_1_2_7_27_2","unstructured":"AtemaJJ GansSL BoermeesterMA(2014) Systematic review and meta\u2010analysis of the open abdomen and temporary abdominal closure techniques in non\u2010trauma patients.World J Surg. doi:10.1007\/s00268\u2010014\u20102883\u20106"},{"issue":"1725","key":"e_1_2_7_28_2","first-page":"2","article-title":"Vacuum and mesh\u2010mediated fascial traction for primary closure of the open abdomen in critically ill surgical patients","volume":"99","author":"Rasilainen SK","year":"2012","journal-title":"Br J Surg"},{"issue":"735","key":"e_1_2_7_29_2","first-page":"3","article-title":"Multicentre prospective study of fascial closure rate after open abdomen with vacuum and mesh\u2010mediated fascial traction","volume":"98","author":"Acosta S","year":"2011","journal-title":"Br J Surg"},{"issue":"60","key":"e_1_2_7_30_2","first-page":"4","article-title":"Early results after treatment of open abdomen after aortic surgery with mesh traction and vacuum\u2010assisted wound closure","volume":"40","author":"Seternes A","year":"2010","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"e_1_2_7_31_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00423\u2010015\u20101370\u20103"},{"issue":"3112","key":"e_1_2_7_32_2","first-page":"4","article-title":"Evaluation of the open abdomen classification system: a validity and reliability analysis","volume":"38","author":"Bjarnason T","year":"2014","journal-title":"World J Surg"},{"issue":"1154","key":"e_1_2_7_33_2","first-page":"9","article-title":"Management of the open abdomen: a national study of clinical outcome and safety of negative pressure wound therapy","volume":"257","author":"Carlson GL","year":"2013","journal-title":"Ann Surg"},{"key":"e_1_2_7_34_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1993.03510240069035"},{"key":"e_1_2_7_35_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01709751"},{"key":"e_1_2_7_36_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010198401000\u201000005"},{"key":"e_1_2_7_37_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134\u2010006\u20100349\u20105"},{"key":"e_1_2_7_38_2","doi-asserted-by":"publisher","DOI":"10.1186\/2110-5820-2-S1-S10"},{"key":"e_1_2_7_39_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054\u2010016\u20101337\u2010y"},{"issue":"487","key":"e_1_2_7_40_2","first-page":"1","article-title":"Topical negative\u2010pressure therapy for small bowel leakage in a frozen abdomen: a technical report","volume":"75","author":"Rekstad LC","year":"2013","journal-title":"J Trauma Acute Care Surg"},{"key":"e_1_2_7_41_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ta.0000203588.66012.c4"},{"key":"e_1_2_7_42_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e2843"},{"key":"e_1_2_7_43_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010009\u20109996\u20103"},{"key":"e_1_2_7_44_2","doi-asserted-by":"publisher","DOI":"10.1177\/1457496916631853"},{"key":"e_1_2_7_45_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181b9e9b1"},{"key":"e_1_2_7_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2006.12.039"},{"key":"e_1_2_7_47_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010013\u20102080\u2010z"},{"key":"e_1_2_7_48_2","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e31827891ce"},{"key":"e_1_2_7_49_2","doi-asserted-by":"crossref","unstructured":"BobkiewiczA WalczakD Smoli\u0144skiS et al. (2016) Management of enteroatmospheric fistula with negative pressure wound therapy in open abdomen treatment: a multicentre observational study.Int Wound J","DOI":"10.1111\/iwj.12597"},{"issue":"20","key":"e_1_2_7_50_2","first-page":"4","article-title":"Treatment of small\u2010bowel fistulae in the open abdomen with topical negative\u2010pressure therapy","volume":"202","author":"D\u2019Hondt M","year":"2011","journal-title":"Am J Surg"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-016-3694-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-016-3694-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-016-3694-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-016-3694-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T16:50:57Z","timestamp":1703609457000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-016-3694-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,19]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1007\/s00268-016-3694-8"],"URL":"https:\/\/doi.org\/10.1007\/s00268-016-3694-8","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,19]]},"assertion":[{"value":"19 August 2016","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Arne Seternes, Martin Bj\u00f6rck, Lars Cato Rekstad, Skule Mo, P\u00e5l Klepstad, Dag L. Halvorsen, Torbj\u00f8rn Dahl and Arne Wibe declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}