{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:11:44Z","timestamp":1787501504934,"version":"build-2736575974"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,11,22]],"date-time":"2016-11-22T00:00:00Z","timestamp":1479772800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2016,11,22]],"date-time":"2016-11-22T00:00:00Z","timestamp":1479772800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients undergoing surgery often use Dietary and Herbal Supplements (DHS). We explored the risk of DHS\u2013drug interactions in the perioperative setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this cross\u2010sectional prospective study, participants hospitalized for surgery completed a questionnaire regarding DHS use. We used pharmacological databases to assess DHS\u2013drug interactions. We then applied univariate and multivariate logistic regression analyses to characterize patients at risk for DHS\u2013drug interactions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 526\u00a0interviewees, 230 (44%) patients reported DHS use, with 16.5% reporting using DHS that could potentially interact with anesthesia. Twenty\u2010four (10%) patients used DHS that could potentially interact with antithrombotic drugs taken perioperatively. The medical files of three patients included reports of intraoperative bleeding. The patient files of only 11% of DHS users documented DHS use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>DHS use poses a significant health risk due to potential interactions. Guidelines should emphasize perioperative management of DHS use.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00268-016-3825-2","type":"journal-article","created":{"date-parts":[[2016,11,22]],"date-time":"2016-11-22T13:14:23Z","timestamp":1479820463000},"page":"927-934","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Perioperative Risks of Dietary and Herbal Supplements"],"prefix":"10.1002","volume":"41","author":[{"given":"Ilana","family":"Levy","sequence":"first","affiliation":[{"name":"Internal Medicine B Department Bnai Zion Medical Center Golomb 47 3339419 Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Attias","sequence":"additional","affiliation":[{"name":"Complementary Medicine Department Bnai Zion Medical Center Haifa Israel"},{"name":"School of Public Health University of Haifa Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eran","family":"Ben\u2010Arye","sequence":"additional","affiliation":[{"name":"Rappaport Faculty of Medicine The Technion\u2010Israel Institute of Technology Haifa Israel"},{"name":"Integrative Oncology Program, Oncology Service, Lin Medical Center Clalit Health Services Western Galilee District, Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee","family":"Goldstein","sequence":"additional","affiliation":[{"name":"Rappaport Faculty of Medicine The Technion\u2010Israel Institute of Technology Haifa Israel"},{"name":"Clinical Pharmacology Unit Haemek Medical Center Afula Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim","family":"Matter","sequence":"additional","affiliation":[{"name":"Rappaport Faculty of Medicine The Technion\u2010Israel Institute of Technology Haifa Israel"},{"name":"Surgery Department Bnai Zion Medical Center Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mostafa","family":"Somri","sequence":"additional","affiliation":[{"name":"Rappaport Faculty of Medicine The Technion\u2010Israel Institute of Technology Haifa Israel"},{"name":"Anesthesiology Department Bnai Zion Medical Center Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elad","family":"Schiff","sequence":"additional","affiliation":[{"name":"Internal Medicine B Department Bnai Zion Medical Center Golomb 47 3339419 Haifa Israel"},{"name":"Complementary Medicine Department Bnai Zion Medical Center Haifa Israel"},{"name":"Rappaport Faculty of Medicine The Technion\u2010Israel Institute of Technology Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,22]]},"reference":[{"key":"e_1_2_9_2_2","unstructured":"Dietary Supplements Health and Education Act(1994)https:\/\/ods.od.nih.gov\/About\/dshea_wording.aspx. Accessed June 15 2015"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542\u2010200007000\u201000025"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0952\u20108180(00)00195\u20101"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000539\u2010200110000\u201000053"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1741\u20107015\u201011\u2010222"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2007.06.030"},{"issue":"10","key":"e_1_2_9_8_2","first-page":"1266","article-title":"Drug\u2010drug interactions: how scared should we be?","volume":"161","author":"Shapiro LE","year":"1999","journal-title":"CMAJ"},{"issue":"2","key":"e_1_2_9_9_2","first-page":"183","article-title":"Perioperative analgesia and the effects of dietary supplements","volume":"28","author":"Abe A","year":"2014","journal-title":"J Clin Anesth"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.2.208"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542\u2010200609000\u201000007"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcae.2014.02.004"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctim.2014.01.005"},{"key":"e_1_2_9_14_2","unstructured":"Natural Medicines Comprehensive Database.http:\/\/naturaldatabase.therapeuticresearch.com. Accessed June 15 2015"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1H423"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2006.09.009"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0091\u20103057(03)00108\u20104"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006\u20102952(00)00264\u20101"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0091\u20103057(02)00777\u20103"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542\u2010197201000\u201000007"},{"key":"e_1_2_9_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.08.039"},{"key":"e_1_2_9_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.plefa.2003.12.004"},{"key":"e_1_2_9_23_2","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20102006\u2010957066"},{"key":"e_1_2_9_24_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1650398"},{"key":"e_1_2_9_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00262088"},{"key":"e_1_2_9_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102044.1991.tb09754.x"},{"key":"e_1_2_9_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2005.05.095"},{"key":"e_1_2_9_28_2","unstructured":"CochraneML(2015) Inhibition of cytochrome P450 2C9 by essential oils.Medical Sciences Thesis"},{"key":"e_1_2_9_29_2","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0b013e3281f8d0eb"},{"key":"e_1_2_9_30_2","unstructured":"Practice Guidelines for Perioperative Blood Management.http:\/\/www.asahq.org\/quality\u2010and\u2010practice\u2010management\/standards\u2010and\u2010guidelines\/search?q=herb. Accessed Sept 12 2015"},{"key":"e_1_2_9_31_2","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0b013e32832f0878"},{"key":"e_1_2_9_32_2","unstructured":"WirsanskyI(2012)Educational interventions for developing awareness and imparting skill questioning about use of dietary and herbal supplements among hospitalized patients. Fundamental Sciences MD Thesis. Technion"},{"key":"e_1_2_9_33_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11\u20102298"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-016-3825-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-016-3825-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-016-3825-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-016-3825-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T11:55:50Z","timestamp":1703591750000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-016-3825-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,22]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["10.1007\/s00268-016-3825-2"],"URL":"https:\/\/doi.org\/10.1007\/s00268-016-3825-2","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,22]]}}}