{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T12:33:11Z","timestamp":1771331591746,"version":"3.50.1"},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,11,28]],"date-time":"2016-11-28T00:00:00Z","timestamp":1480291200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2016,11,28]],"date-time":"2016-11-28T00:00:00Z","timestamp":1480291200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Performing routine prophylactic cholecystectomy during gastrectomy in gastric cancer patients has been controversial. The frequency of cholelithiasis, cholecystitis, and cholangitis after gastrectomy has not been reported for large patient populations, so we carried out this retrospective study to aid the assessment of the necessity for prophylactic cholecystectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective study reviewed 969 patients with gastric cancer who underwent distal gastrectomies with Billroth I reconstructions (DG) or total gastrectomies with Roux\u2010en\u2010Y reconstructions (TG), preserving the gallbladder, between January 2000 and May 2012. Risk factors for cholelithiasis, cholecystitis, and cholangitis after gastrectomy were evaluated using logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median follow\u2010up period after gastrectomy was 48\u00a0months (range 12\u2013159\u00a0months). After gastrectomy, cholelithiasis occurred in 6.1% (59\/969) patients and cholecystitis and\/or cholangitis occurred in 1.2% (12\/969) patients. The method used for gastrectomy was an independent risk factor for both cholelithiasis (TG\/DG: OR (95%CI): 1.900 (1.114\u20133.240), <jats:italic>p<\/jats:italic> = 0.018) and cholecystitis and\/or cholangitis (TG\/DG: OR (95%CI): 8.325 (1.814\u201338.197), <jats:italic>p<\/jats:italic> = 0.006). In patients who developed cholelithiasis, the incidence of cholecystitis and\/or cholangitis was 31.3% (10\/32) after TG, but only 7.4% after DG.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Prophylactic cholecystectomy may be unnecessary in distal gastrectomy with Billroth I reconstruction.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-016-3831-4","type":"journal-article","created":{"date-parts":[[2016,11,28]],"date-time":"2016-11-28T16:56:18Z","timestamp":1480352178000},"page":"1047-1053","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Is Routine Prophylactic Cholecystectomy Necessary During Gastrectomy for Gastric Cancer?"],"prefix":"10.1002","volume":"41","author":[{"given":"Jun","family":"Kimura","sequence":"first","affiliation":[{"name":"Department of Surgery, Gastroenterological Center Yokohama City University Medical Center Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chikara","family":"Kunisaki","sequence":"additional","affiliation":[{"name":"Department of Surgery, Gastroenterological Center Yokohama City University Medical Center Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryo","family":"Takagawa","sequence":"additional","affiliation":[{"name":"Department of Surgery, Gastroenterological Center Yokohama City University Medical Center Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirochika","family":"Makino","sequence":"additional","affiliation":[{"name":"Department of Surgery, Gastroenterological Center Yokohama City University Medical Center Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michio","family":"Ueda","sequence":"additional","affiliation":[{"name":"Department of Surgery, Gastroenterological Center Yokohama City University Medical Center Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuyoshi","family":"Ota","sequence":"additional","affiliation":[{"name":"Department of Surgery, Gastroenterological Center Yokohama City University Medical Center Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari","family":"Oba","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Epidemiology, Graduate School of Medicine Yokohama City University Medical Center Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Kosaka","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Medicine Yokohama City University Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotoshi","family":"Akiyama","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Medicine Yokohama City University Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Itaru","family":"Endo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Graduate School of Medicine Yokohama City University Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,11,28]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.5117"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39267.452257.AD"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10620\u2010006\u20109107\u20103"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11605\u2010009\u20100832\u20108"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00311307"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01537576"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1159\/000129433"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010004\u20107482\u20105"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010198503000\u201000010"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199201000-00002"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102036.2000.014s2035.x"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1984.01390240027005"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02470844"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800770522"},{"key":"e_1_2_7_16_2","unstructured":"Japanese Gastric Cancer Association(2001)Japanese gastric cancer treatment guidelines. 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