{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T09:00:36Z","timestamp":1770973236295,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T00:00:00Z","timestamp":1488412800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T00:00:00Z","timestamp":1488412800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The role of preoperative imaging and the usability of different imaging modalities is highly variable and controversial in reduction mammaplasty patients. Our study describes the imaging process in a single center in regard to modality selection, age and timing, and of the association between imaging and histopathological findings in reduction mammaplasty specimens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Nine hundred eighteen women, who underwent reduction mammaplasty during 1.1.2007\u201331.12.2011, were retrospectively reviewed for demographics, preoperative imaging, further preoperative examinations, and pathology reports.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Preoperative imaging had been conducted for 89.2% (<jats:italic>n<\/jats:italic> = 819) of the patients. In 49 (6.0%) patients, suspicious preoperative imaging led to further examinations revealing 2 high\u2010risk lesions (atypical ductal hyperplasia (ADH), lobular carcinoma in situ (LCIS)), and 2 cancers preoperatively. Postoperatively abnormal histopathology specimens were revealed in 88 (10.4%) patients. The incidence of high\u2010risk lesions was 5.5% (<jats:italic>n<\/jats:italic> = 47), and the incidence of cancer was 1.2% (<jats:italic>n<\/jats:italic> = 10). Preoperative imaging was normal (BI\u2010RADS 1 and BI\u2010RADS 2) in 80.8% of these patients. The sensitivity of the preoperative imaging for cancer detection was 20.0%, and the specificity was 100.0%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Preoperative imaging and further examinations do not sufficiently detect malignant or cancer risk\u2010increasing findings. Therefore, histopathological analysis of reduction mammaplasty specimens seems mandatory.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-017-3920-z","type":"journal-article","created":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T15:36:32Z","timestamp":1488468992000},"page":"2013-2019","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Breast Cancer Detection by Preoperative Imaging in Reduction Mammaplasty Patients: A Single Center Study of 918\u00a0Patients"],"prefix":"10.1002","volume":"41","author":[{"given":"P\u00e4ivi A.","family":"Merkkola\u2010von Schantz","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery University of Helsinki and Helsinki University Hospital P.O. Box 266 00029 Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanna M. C.","family":"Kauhanen","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery University of Helsinki and Helsinki University Hospital P.O. Box 266 00029 Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiina A.","family":"Jahkola","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery University of Helsinki and Helsinki University Hospital P.O. Box 266 00029 Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leena A.","family":"Krogerus","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Helsinki and Helsinki University Hospital P.O. Box 800 00029 Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katja S.","family":"Hukkinen","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Helsinki and Helsinki University Hospital P.O. 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