{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T23:13:32Z","timestamp":1785798812414,"version":"3.56.0"},"reference-count":10,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,4,20]],"date-time":"2017-04-20T00:00:00Z","timestamp":1492646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2017,4,20]],"date-time":"2017-04-20T00:00:00Z","timestamp":1492646400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The most frequent recurrence site of papillary thyroid carcinoma (PTC) is the cervical lymph nodes. The introduction of an electric linear probe for use with ultrasonography in 1996 improved preoperative lateral neck evaluations. Before 2006, however, our hospital routinely performed prophylactic modified neck dissection (p\u2010MND) for N0 or N1a PTCs &gt;1\u00a0cm to prevent node recurrence. In 2006, we changed our policy and the indications for p\u2010MND to PTCs &gt;3\u00a0cm and\/or with significant extrathyroid extension. Here, we retrospectively compared lymph node recurrence\u2010free survival between PTCs with\/without p\u2010MND.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We examined the cases of N0 or N1 and M0\u00a0PTC patients who underwent initial surgery in 1992\u20132012. To compare lymph node recurrence\u2010free survival between patients who did\/did not undergo p\u2010MND, we divided these patients into three groups (excluding those whose surgery was in 2006): the 2045 patients whose surgery was performed in 1992\u20131996 (Group 1), the 2989 with surgery between 1997 (post\u2010introduction of ultrasound electric linear probes) and 2005 (Group 2), and the 5332 operated on in 2007\u20132012 (Group 3).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The p\u2010MND performance rate of Group 3 (9%) was much lower than that of Group 1 (80%), but the lymph node recurrence\u2010free survival of the former was significantly better, probably due to differences in clinical features and neck evaluations by ultrasound between the two groups. Our analysis of the patients aged &lt;75 years with 1.1\u20134\u2010cm PTCs in Groups 2 and 3 showed that p\u2010MND did not improve lymph node recurrence\u2010free survival. p\u2010MND did significantly improve lymph node recurrence\u2010free survival for the extrathyroid extension\u2010positive 3.1\u20134\u2010cm PTCs, but not for the other subsets.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Abolishing routine p\u2010MND for PTCs in 2006 did not decrease lymph node recurrence\u2010free survival, probably due to improved ultrasound preoperative neck evaluations and clinical feature changes. Selective p\u2010MND for high\u2010risk cases improved lymph node recurrence\u2010free survival.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-017-4023-6","type":"journal-article","created":{"date-parts":[[2017,4,20]],"date-time":"2017-04-20T16:46:40Z","timestamp":1492706800000},"page":"2283-2289","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["The Effectiveness of Prophylactic Modified Neck Dissection for Reducing the Development of Lymph Node Recurrence of Papillary Thyroid Carcinoma"],"prefix":"10.1002","volume":"41","author":[{"given":"Yasuhiro","family":"Ito","sequence":"first","affiliation":[{"name":"Department of Surgery Kuma Hospital 8\u20102\u201035, Shimoyamate\u2010dori, Chuo\u2010ku 650\u20100011 Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Miyauchi","sequence":"additional","affiliation":[{"name":"Department of Surgery Kuma Hospital 8\u20102\u201035, Shimoyamate\u2010dori, Chuo\u2010ku 650\u20100011 Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takumi","family":"Kudo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kuma Hospital Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minoru","family":"Kihara","sequence":"additional","affiliation":[{"name":"Department of Surgery Kuma Hospital 8\u20102\u201035, Shimoyamate\u2010dori, Chuo\u2010ku 650\u20100011 Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuhiro","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Department of Surgery Kuma Hospital 8\u20102\u201035, Shimoyamate\u2010dori, Chuo\u2010ku 650\u20100011 Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Miya","sequence":"additional","affiliation":[{"name":"Department of Surgery Kuma Hospital 8\u20102\u201035, Shimoyamate\u2010dori, Chuo\u2010ku 650\u20100011 Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,4,20]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010010\u20100832\u20106"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010004\u20107701\u20100"},{"key":"e_1_2_6_4_2","volume-title":"UICC: TNM classification of malignant tumors","author":"Sobin LH","year":"2009"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010007\u20109224\u2010y"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010008\u20109711\u20109"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1089\/105072503322021142"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.EJ12\u20100311"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010012\u20101423\u20105"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010006\u20100722\u20100"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010005\u20107722\u20103"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-017-4023-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-017-4023-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-017-4023-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-017-4023-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T23:28:50Z","timestamp":1704929330000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-017-4023-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,20]]},"references-count":10,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1007\/s00268-017-4023-6"],"URL":"https:\/\/doi.org\/10.1007\/s00268-017-4023-6","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,20]]}}}