{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T12:29:26Z","timestamp":1754396966335},"reference-count":28,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,5,5]],"date-time":"2017-05-05T00:00:00Z","timestamp":1493942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2017,5,5]],"date-time":"2017-05-05T00:00:00Z","timestamp":1493942400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Iron deficiency can occur in patients after Roux\u2010en\u2010y gastric bypass due to altered absorption. Pica, the compulsive craving and intake of non\u2010nutritive substances, is a rare and poorly understood presentation of iron deficiency. To our knowledge, the rate of pica after RYGB has never been reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The medical records of patients who underwent laparoscopic RYGB from 2001 to 2011 were reviewed. Patients with pica or other abnormal cravings were identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Pica was identified in 16\/959 (1.7%) patients who underwent RYGB during the study period. The most common presenting sign was pagophagia. All patients with pica were female and had multiple risk factors for iron deficiency with 13\/16 being premenopausal and 7\/16\u00a0non\u2010compliant with oral iron supplementation. Pica symptoms presented at a mean of 3.9 \u00b1 1.9 years after RYGB. Iron deficiency was identified in all 16 patients, with a median ferritin level of 5.0\u00a0ng\/mL (range 2\u201327). All 16 patients received intravenous iron and pica symptoms resolved.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Pica is a rare phenomenon associated with iron deficiency and can occur despite oral iron supplementation. In our experience, intravenous iron can relieve symptoms. Patients considering bariatric surgery should be counseled on pica. Patients with unusual cravings should be evaluated for iron deficiency.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-017-4048-x","type":"journal-article","created":{"date-parts":[[2017,5,5]],"date-time":"2017-05-05T16:31:34Z","timestamp":1494001894000},"page":"2324-2328","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A Different Kind of Craving: Incidence and Treatment of Pica After Laparoscopic Roux\u2010en\u2010Y Gastric Bypass"],"prefix":"10.1002","volume":"41","author":[{"given":"Andrew D.","family":"Van Osdol","sequence":"first","affiliation":[{"name":"Minimally Invasive Bariatric Surgery and Advanced Laparoscopy Fellowship, Department of Medical Education Gundersen Medical Foundation La Crosse WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kara J.","family":"Kallies","sequence":"additional","affiliation":[{"name":"Department of Medical Research Gundersen Medical Foundation La Crosse WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyla A.","family":"Fredrickson","sequence":"additional","affiliation":[{"name":"Department of Medical Research Gundersen Medical Foundation La Crosse WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shanu N.","family":"Kothari","sequence":"additional","affiliation":[{"name":"Department of General Surgery Gundersen Health System 1900 South Avenue, C05\u2010001 54601 La Crosse WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,5,5]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700038022"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002\u20109343(94)90309\u20103"},{"key":"e_1_2_7_5_2","first-page":"206","article-title":"Food habits during pregnancy among Saudi women","volume":"65","author":"Al\u2010Kanhal MA","year":"1995","journal-title":"Int J Vitam Nutr Res"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002\u20109343(00)00396\u2010X"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2004.07.050"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003\u20104819\u201069\u20103\u2010435"},{"key":"e_1_2_7_9_2","first-page":"321","article-title":"Rapid regression of prolonged pagophagia after treatment of iron deficiency","volume":"30","author":"Sontag C","year":"2001","journal-title":"Presse Med"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/2327-6924.12268"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2326-10-9"},{"key":"e_1_2_7_12_2","unstructured":"American Society for Metabolic and Bariatric Surgery.Bariatric surgery procedures.https:\/\/asmbs.org\/patients\/bariatric\u2010surgery\u2010procedures. Last Accessed 2017"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2015.08.496"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2008.03.002"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2013.10.023"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood\u20102011\u201004\u2010346304"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.228874"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jada.2004.06.026"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1381\/096089205774859371"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025\u20106196(11)60774\u2010X"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003\u20104819\u2010115\u201012\u2010956"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2009.09.004"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1177\/2045125314561221"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12061"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1179\/1607845414Y.0000000219"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.3945\/jn.114.192070"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10803\u2010015\u20102375\u2010z"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22279"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu6093587"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-017-4048-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-017-4048-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-017-4048-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-017-4048-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T23:28:06Z","timestamp":1704929286000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-017-4048-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,5]]},"references-count":28,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1007\/s00268-017-4048-x"],"URL":"https:\/\/doi.org\/10.1007\/s00268-017-4048-x","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,5]]}}}