{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T08:36:11Z","timestamp":1790843771119,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,1,2]],"date-time":"2019-01-02T00:00:00Z","timestamp":1546387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,1,2]],"date-time":"2019-01-02T00:00:00Z","timestamp":1546387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"MacKay Medical College and MacKay Memorial Hospital, Taiwan","award":["107DMH0100277"],"award-info":[{"award-number":["107DMH0100277"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2019,5,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Bloodstream infections (BSI) are an important source of postoperative mortality in hepatobiliary\u2013pancreatic surgery (HBPS) patients, and no prediction model has been analyzed before.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using big data from the electronic medical records of the administrative and culture databases of MacKay Memorial Hospital, we identified the potential risk factors for community\u2010acquired and healthcare\u2010associated BSI and mortality of patients who received HBPS. Subsequently, we analyzed the microorganisms\u2019 profiles and antimicrobial susceptibility patterns for these BSI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>BSI were found in 6.3% patients (349 of 5513 HBPS patients), and hospital mortality was 1.48% (82 of 5513). Dividing patients into low\u2010, intermediate\u2010, and high\u2010risk groups on the basis of sex, age, status of comorbidity (renal failure, peptic ulcer disease, fluid and electrolyte disorders, and acute cholecystitis), a predictive BSI risk score model was developed. According to this model, BSI risk ranged from 1.43% to 11.95%; AUROC to predict BSI risk was 0.72 (95% CI 0.69\u20130.75). From this retrospective study, Enterobacteriaceae were the most common microorganisms that were isolated from BSI. For both community\u2010acquired and healthcare\u2010associated BSI, imipenem and colistin are the most successful.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This novel model can be useful to predict who is at risk of BSI after HBPS, and new prophylactic protocols for these patients are needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00268-018-04903-x","type":"journal-article","created":{"date-parts":[[2019,1,2]],"date-time":"2019-01-02T15:45:44Z","timestamp":1546443944000},"page":"1294-1302","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["A Novel Prediction Model for Bloodstream Infections in Hepatobiliary\u2013Pancreatic Surgery Patients"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6226-2618","authenticated-orcid":false,"given":"Po\u2010Sheng","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Medicine MacKay Medical College No. 46, Sec. 3, Zhongzheng Rd., Sanzhi Dist. 252 New Taipei City Taiwan"},{"name":"Department of General Surgery MacKay Memorial Hospital Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang\u2010Pan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Infection Control Center MacKay Memorial Hospital Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010Chiung","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences and Engineering National Central University Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuen\u2010Fei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Medicine MacKay Medical College No. 46, Sec. 3, Zhongzheng Rd., Sanzhi Dist. 252 New Taipei City Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi\u2010Chan","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of General Surgery MacKay Memorial Hospital Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih\u2010Ping","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Medicine MacKay Medical College No. 46, Sec. 3, Zhongzheng Rd., Sanzhi Dist. 252 New Taipei City Taiwan"},{"name":"Department of General Surgery MacKay Memorial Hospital Taipei 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