{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T21:13:22Z","timestamp":1790630002972,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,3,8]],"date-time":"2018-03-08T00:00:00Z","timestamp":1520467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2018,3,8]],"date-time":"2018-03-08T00:00:00Z","timestamp":1520467200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Gallbladder cancer (GBC) is a rare tumor in developed countries. Chile has one of the highest incidences worldwide. For patients affected by resectable T1b or more advanced GBC, radical cholecystectomy (RC) is considered the standard therapy. Our aim is to describe the surgical technique and clinical\u2013pathological results of patients undergoing totally laparoscopic radical resection of GBC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients undergo laparoscopic radical resection for primary and incidental GBC, between the years 2009 and 2016\u00a0in two centers from Chile. Patients in whom suspected bile duct invasion, frozen biopsy did not confirm cancer and para\u2010aortic lymph node sampling was positive were excluded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eighteen patients were operated, 77.8% were female with median age of 60.5 year, and 16 patients had previous cholecystectomy with incidental cancer finding. The median operative time was 490\u00a0min (400\u2013550). No conversion to open surgery occurred. All patients achieved a R0 resection. Postoperative complications occurred in 2 patients (11.1%), and there was not mortality. After a median follow\u2010up of 59\u00a0months, the 5\u2010year survival was 80.7%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study shows the technical feasibility of the totally laparoscopic approach for radical resection of GBC with the same principles of classical open surgery. It appears that long\u2010term oncological findings would also be similar at least in less advanced lesions.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-018-4490-4","type":"journal-article","created":{"date-parts":[[2018,3,8]],"date-time":"2018-03-08T14:31:36Z","timestamp":1520519496000},"page":"2592-2598","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Totally Laparoscopic Radical Resection of Gallbladder Cancer: Technical Aspects and Long\u2010Term Results"],"prefix":"10.1002","volume":"42","author":[{"given":"C\u00e9sar Mu\u00f1oz","family":"Castro","sequence":"first","affiliation":[{"name":"Digestive Surgery Hospital Regional de Talca 1 North #1951 Talca Chile"},{"name":"Medicine School Universidad Cat\u00f3lica del Maule Talca Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio Pacheco","family":"Santiba\u00f1ez","sequence":"additional","affiliation":[{"name":"Digestive 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