{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T03:20:18Z","timestamp":1773285618107,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2018,6,29]],"date-time":"2018-06-29T00:00:00Z","timestamp":1530230400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2018,6,29]],"date-time":"2018-06-29T00:00:00Z","timestamp":1530230400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Surgical site infection is very uncommon after pyloromyotomy in children, and it is considered a \u201cclean\u201d procedure under the traditional wound classification system. This study aims to investigate prophylactic antibiotic administration for pyloromyotomy among children\u2019s hospitals in the USA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The Pediatric Health Information System (PHIS) database was retrospectively reviewed from 2014 to 2015\u00a0including all patients less than 1 year old who had a principal diagnosis of pyloric stenosis and underwent pyloromyotomy. Patient demographics, hospital length of stay, and perioperative antibiotic administration were extracted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 4206 patients met study criteria. Most patients were male (84%) and Caucasian (70%). The median age at admission was 32\u00a0days (IQR 24\u201344\u00a0days), and median length of stay was 2\u00a0days (IQR 1\u20132\u00a0days). Antibiotics were administered perioperatively in 2153 (51%) patients with marked variation among children\u2019s hospitals. Antibiotics were given to more than 10% of patients in more than 90% of hospitals, and only two of 49 hospitals gave no antibiotic prophylaxis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study has shown that at several tertiary\u2010level children\u2019s hospitals in the USA, antibiotic prophylaxis is administered for pyloromyotomy, a \u201cclean\u201d procedure. This highlights the need for standardization of care and more effective antibiotic stewardship in pediatric surgery.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-018-4729-0","type":"journal-article","created":{"date-parts":[[2018,6,29]],"date-time":"2018-06-29T14:20:59Z","timestamp":1530282059000},"page":"4107-4111","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Antibiotic Prophylaxis for Pyloromyotomy in Children: An Opportunity for Better Stewardship"],"prefix":"10.1002","volume":"42","author":[{"given":"Kibileri","family":"Williams","sequence":"first","affiliation":[{"name":"Howard University Hospital 2041 Georgia Ave NW 20001 Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy","family":"Lautz","sequence":"additional","affiliation":[{"name":"Ann &amp; Robert H. Lurie Children\u2019s Hospital of Chicago 225 E. Chicago Ave, Box 63 60611 Chicago IL USA"},{"name":"Northwestern University Feinberg School of Medicine 420 E. Superior St 60611 Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard J.","family":"Hendrickson","sequence":"additional","affiliation":[{"name":"Department of Surgery Children\u2019s Mercy Kansas City 2401 Gillham Rd 64108 Kansas City MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tolulope A.","family":"Oyetunji","sequence":"additional","affiliation":[{"name":"Department of Surgery Children\u2019s Mercy Kansas City 2401 Gillham Rd 64108 Kansas City MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,6,29]]},"reference":[{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1086\/499406"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1086\/673982"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010\u20101275"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2016.0019"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.08.115"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2011.03.037"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2016.07.010"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013\u20101243"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1072\u20107515(99)00136\u20102"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2007.12.075"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2005.03.012"},{"issue":"3","key":"e_1_2_10_13_2","first-page":"178","article-title":"Antibiotic prophylaxis for infantile pyloromyotomy","volume":"41","author":"Nour S","year":"1996","journal-title":"J R Coll Surg Edinb"},{"key":"e_1_2_10_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2016.05.006"},{"key":"e_1_2_10_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010012\u20102174\u2010y"},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2009.04.001"},{"key":"e_1_2_10_17_2","unstructured":"Prevention CfDCa(2013)Antibiotic Resistance Threats in the US.https:\/\/www.cdc.gov\/features\/antibioticresistancethreats\/index.html. 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The authors report no proprietary or commercial interest in any product mentioned or concept discussed in this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}