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Identifying risk factors that can prognosticate outcome is critical to obtain the best management practices for patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study was performed for patients who were diagnosed with CDH from November 2000 to August 2016. A total of 10 prenatal risk factors and 14 postnatal risk factors were analyzed. All postnatal variables were measured within 24 h after birth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 95 CDH patients were enrolled in this study, including 61\u00a0males and 34 females with mean gestational age of 38.86\u2009\u00b1\u20091.51 weeks. The overall 30\u2010day survival rate was 63.2%. Multivariate analysis revealed that five factors (polyhydramnios, gestational age at diagnosis &lt;25 weeks, observed\u2010to\u2010expected lung\u2010to\u2010head ratio \u226445, best oxygenation index in 24 h\u2009 &gt;11, and severity of tricuspid regurgitation\u2009\u2265\u2009mild) were independent predictors of 30\u2010day mortality of CDH. Using these five factors, a perinatal prognostic index for 30\u2010day mortality was developed. Four predictive models (poor, bad, good, and excellent) of the perinatal prognostic index were constructed, and external validation was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Awareness of risk factors is very important for predicting prognosis and managing patients. Five independent perinatal risk factors were identified in this study. A perinatal prognostic index was developed for 30\u2010day mortality for patients with CDH. This index may be used to help manage CDH patients.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-018-4780-x","type":"journal-article","created":{"date-parts":[[2018,8,30]],"date-time":"2018-08-30T14:01:38Z","timestamp":1535637698000},"page":"282-290","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Predicting Survival of Congenital Diaphragmatic Hernia on the First Day of Life"],"prefix":"10.1002","volume":"43","author":[{"given":"Chaeyoun","family":"Oh","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery Korea University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joong Kee","family":"Youn","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Seoul National University College of Medicine Children\u2019s Hospital 101, Daehang\u2010ro, Yeongeon\u2010dong, Jongro\u2010Gu 03080 Seoul 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