{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:18:44Z","timestamp":1786979924562,"version":"build-2736575974"},"reference-count":35,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T00:00:00Z","timestamp":1540252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T00:00:00Z","timestamp":1540252800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2019,3,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Transcutaneous laryngeal ultrasound (TLUSG) is an innovative, non\u2010invasive tool in detecting post\u2010thyroidectomy vocal cord palsy (VCP). However, TLUSG failed to detect about 6\u201315% laryngoscopic examination (LE)\u2010confirmed VCP. It is unclear whether the outcome of patients with VCP missed by TLUSG [false negative (FN)] is different from those with VCP diagnosed by TLUSG [true positive (TP)]. Therefore, this study aimed to compare the clinical outcome and prognosis between patients with FN results and TP results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Over 46\u00a0months, all consecutive patients undergoing thyroidectomy or endocrine\u2010related neck procedure were recruited. They underwent pre\u2010operative and post\u2010operative voice assessments on symptoms, voice\u2010specific questionnaire [voice handicap index questionnaire (VHI\u201030)], TLUSG and LE. For patients with post\u2010operative vocal cord palsy, reassessment LE would be arranged at second, fourth, sixth and twelfth months post\u2010operatively until VCP recovered.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 1196 patients, including 74 post\u2010thyroidectomy VCP, were recruited. For those with assessable vocal cords (VC), 58 VCP were correctly diagnosed by TLUSG (TP) and 10 VCP were missed by TLUSG (FN). Sensitivity and specificity of detecting a VCP by TLUSG were 85.3% and 94.7%, respectively. VHI\u201030 score was significantly increased after operation in TP group [31 (range \u2212\u20096\u2013105),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001] but not in FN group [20 (14\u201399),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.089]. Comparing to TP group, VCP recovered earlier (69 vs. 125\u00a0days,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and less patients suffered from permanent VCP in patients with FN results. (34.5% vs. 0.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.027).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The VCP missed by TLUSG had a milder course of disease. Early recovery of VC function and non\u2010permanent palsy were expected.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00268-018-4826-0","type":"journal-article","created":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T20:12:46Z","timestamp":1540325566000},"page":"824-830","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Vocal Cord Palsies Missed by Transcutaneous Laryngeal Ultrasound (TLUSG): Do They Experience Worse Outcomes?"],"prefix":"10.1002","volume":"43","author":[{"given":"Kai\u2010Pun","family":"Wong","sequence":"first","affiliation":[{"name":"Division of Endocrine Surgery, Department of Surgery The University of Hong Kong, Queen Mary Hospital 102 Pokfulam Road Pokfulam Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kin Pan","family":"Au","sequence":"additional","affiliation":[{"name":"Division of Endocrine Surgery, Department of Surgery The University of Hong Kong, Queen Mary Hospital 102 Pokfulam Road Pokfulam Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi","family":"Lam","sequence":"additional","affiliation":[{"name":"Division of Endocrine Surgery, Department of Surgery The University of Hong Kong, Queen Mary Hospital 102 Pokfulam Road Pokfulam Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuk Kwan","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Endocrine Surgery, Department of Surgery The University of Hong Kong, Queen Mary Hospital 102 Pokfulam Road Pokfulam Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian Hung Hin","family":"Lang","sequence":"additional","affiliation":[{"name":"Division of Endocrine Surgery, Department of Surgery The University of Hong Kong, Queen Mary Hospital 102 Pokfulam Road Pokfulam Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,10,23]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21965"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24409"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348941212101102"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24535"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24722"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2014.08.071"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010015\u20103393\u2010x"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2015.2795"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2016.10.013"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.23736\/S0375-9393.17.11755-4"},{"key":"e_1_2_7_12_2","unstructured":"LazardDS Bergeret\u2010CassagneH LefortMet al. 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