{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T12:29:29Z","timestamp":1793017769270,"version":"4.5.0"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,2,4]],"date-time":"2019-02-04T00:00:00Z","timestamp":1549238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2019,2,4]],"date-time":"2019-02-04T00:00:00Z","timestamp":1549238400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,2,4]],"date-time":"2019-02-04T00:00:00Z","timestamp":1549238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2019,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Extracorporeal membrane oxygenation (ECMO) induces coagulation disorders increasing the risk of bleeding during invasive procedures. We aimed to describe the outcomes of critically ill ECMO patients undergoing emergency abdominal surgery compared to non\u2010ECMO patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>This is a retrospective case\u2010matched single\u2010center study with propensity score analysis in a tertiary ICU. All patients who underwent abdominal surgery were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From 2006 to 2014, 77 patients admitted in our ICU underwent emergency abdominal surgery, 35 were on ECMO. Surgery indications were comparable for ECMO and non\u2010ECMO patients: mostly intestinal ischemia (42%) and cholecystectomy (25%). Postoperative bleeding was significantly more frequent in ECMO group versus non\u2010ECMO: 77% versus 40% transfused, with medians of 13 (6\u201322) versus 3 (0\u20135) packed red blood cell; 9 (3\u201317) versus 0 (0\u20134) fresh frozen plasma and 12 (3\u201322) versus 0 (0\u20138) platelet units (<jats:italic>p\u2009<\/jats:italic>&lt;\u20090.001 for all items). Reintervention for hemorrhage was required in 20% versus 2%, respectively, <jats:italic>p\u2009<\/jats:italic>=\u20090.02. At multivariable analysis, ECMO was strongly associated with bleeding (OR, 5.6 [95% CI, 2.0\u201315.4]; <jats:italic>p<\/jats:italic>\u2009=\u20090.001). ICU mortality was higher for ECMO\u2010treated patients (69% vs. 33%; <jats:italic>p<\/jats:italic>\u2009=\u20090.003), but perioperative mortality remained comparable between groups (11% vs. 12%, NS). Propensity score\u2010matched analysis confirmed more frequent and severe bleeding in ECMO patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Abdominal surgery procedures on ECMO\u2010treated patients are associated with a higher risk of hemorrhage compared to non\u2010ECMO ICU patients. Further studies are needed to optimize ECMO patient management during such interventions.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-019-04930-2","type":"journal-article","created":{"date-parts":[[2019,2,4]],"date-time":"2019-02-04T20:48:57Z","timestamp":1549313337000},"page":"1474-1482","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Emergency Abdominal Surgery Outcomes of Critically Ill Patients on Extracorporeal Membrane Oxygenation: A Case\u2010Matched Study with a Propensity Score Analysis"],"prefix":"10.1002","volume":"43","author":[{"given":"Anna","family":"Taieb","sequence":"first","affiliation":[{"name":"Department of Digestive and Endocrine Surgery, H\u00f4pital Piti\u00e9\u2013Salp\u00eatri\u00e8re, Assistance Publique\u2013H\u00f4pitaux de Paris Sorbonne University (Paris 6) Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Jeune","sequence":"additional","affiliation":[{"name":"Department of Digestive and Hepato\u2010Pancreato\u2010Biliary Surgery, H\u00f4pital Piti\u00e9\u2013Salp\u00eatri\u00e8re, Assistance Publique\u2013H\u00f4pitaux de Paris Sorbonne University (Paris 6) Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Said","family":"Lebbah","sequence":"additional","affiliation":[{"name":"Clinical Research Department, H\u00f4pital Piti\u00e9\u2013Salp\u00eatri\u00e8re, Assistance Publique\u2013H\u00f4pitaux de Paris Sorbonne University (Paris 6) Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthieu","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Medical\u2013Surgical ICU, H\u00f4pital Piti\u00e9\u2013Salp\u00eatri\u00e8re, Assistance Publique\u2013H\u00f4pitaux de Paris Sorbonne University (Paris 6) Paris France"},{"name":"INSERM, UMRS_1166\u2010iCAN Institute of Cardiometabolism and Nutrition Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Deransy","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care, H\u00f4pital Piti\u00e9\u2013Salp\u00eatri\u00e8re, Assistance Publique\u2013H\u00f4pitaux de Paris Sorbonne University (Paris 6) Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Christophe","family":"Vaillant","sequence":"additional","affiliation":[{"name":"Department of Digestive and Hepato\u2010Pancreato\u2010Biliary Surgery, H\u00f4pital Piti\u00e9\u2013Salp\u00eatri\u00e8re, Assistance Publique\u2013H\u00f4pitaux de Paris Sorbonne University (Paris 6) Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles\u2010Edouard","family":"Luyt","sequence":"additional","affiliation":[{"name":"Medical\u2013Surgical ICU, H\u00f4pital Piti\u00e9\u2013Salp\u00eatri\u00e8re, Assistance Publique\u2013H\u00f4pitaux de Paris Sorbonne University (Paris 6) Paris France"},{"name":"INSERM, UMRS_1166\u2010iCAN Institute of Cardiometabolism and Nutrition Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Tr\u00e9sallet","sequence":"additional","affiliation":[{"name":"Department of Digestive and Endocrine Surgery, H\u00f4pital Piti\u00e9\u2013Salp\u00eatri\u00e8re, Assistance Publique\u2013H\u00f4pitaux de Paris Sorbonne University (Paris 6) Paris France"},{"name":"INSERM\u2010CNRS U 678\u2010 laboratoire d\u2019imagerie Biom\u00e9dicale (LIB), Departement of General, Visceral and Endocrine Surgery, Groupe Hospitalier Piti\u00e9\u2013Salp\u00eatri\u00e8re Sorbonne University (Paris 6) 47\/83, Boulevard de l\u2019H\u00f4pital 75651 Paris Cedex 13 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