{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T05:08:24Z","timestamp":1776402504124,"version":"3.51.2"},"reference-count":41,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T00:00:00Z","timestamp":1558483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T00:00:00Z","timestamp":1558483200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T00:00:00Z","timestamp":1558483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2019,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To compare the overall survival (OS) and disease\u2010free survival (DFS) of Tourniquet\u2010ALPPS (T\u2010ALPPS) and conventional two\u2010stage hepatectomy (TSH) in patients with colorectal liver metastases (CRLM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study from a prospectively collected database was performed between October 2000 and July 2016. TSH was performed before September 2011, after which time T\u2010ALPPS became the technique of choice. A propensity score matching (PSM) was performed based on a 1:1 ratio with consideration of the following variables: number and size of metastases, bilobar disease presence, and chemotherapy received.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010four patients received T\u2010ALPPS; 41 patients received TSH. After PSM, 21 patients remained in each group, with 100% resectability in the T\u2010ALPPS group and 90.5% resectability in the TSH group. The median OS for TSH was 41\u00a0months; for T\u2010ALPPS, the median OS was 36\u00a0months (<jats:italic>P<\/jats:italic>\u2009=\u20090.925). The median DFS was 16\u00a0months in the TSH group; the median DFS was 9\u00a0months in the T\u2010ALPPS group (<jats:italic>P<\/jats:italic>\u2009=\u20090.930). The 1\u2010, 3\u2010, and 5\u2010year OS for TSH was 81%, 66.7%, and 23.8% vs. 76.2%, 57.1%, and 22.9% for T\u2010ALPPS, respectively. The 1\u2010, 3\u2010, and 5\u2010year DFS for TSH was 66.7%, 9.5%, and 5% vs. 44.6%, 11.1%, and 11.1% for T\u2010ALPPS, respectively. The volume increase with T\u2010ALPPS was superior to that with TSH (68% vs. 39%; <jats:italic>P<\/jats:italic>\u2009=\u20090.018). There were no differences in morbidity and mortality after stages 1 and 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>T\u2010ALPPS produces a similar outcome to TSH, indicating that it could be a safe and effective alternative for curative hepatectomy for all patients.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-019-05031-w","type":"journal-article","created":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T03:40:59Z","timestamp":1558582859000},"page":"2281-2289","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Long\u2010Term Outcome After Conventional Two\u2010Stage Hepatectomy Versus Tourniquet\u2010ALPPS in Colorectal Liver Metastases: A Propensity Score Matching Analysis"],"prefix":"10.1002","volume":"43","author":[{"given":"Ricardo","family":"Robles\u2010Campos","sequence":"first","affiliation":[{"name":"Department of Liver Surgery and Transplantation Virgen de La Arrixaca Clinic, University Hospital, IMIB\u2010Arrixaca Murcia Spain"},{"name":"Department of Surgery Virgen de La Arrixaca Clinic, University Hospital El Palmar, Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Brusadin","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery and Transplantation Virgen de La Arrixaca Clinic, University Hospital, IMIB\u2010Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asunci\u00f3n","family":"L\u00f3pez\u2010Conesa","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery and Transplantation Virgen de La Arrixaca Clinic, University Hospital, IMIB\u2010Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00edctor","family":"L\u00f3pez\u2010L\u00f3pez","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery and Transplantation Virgen de La Arrixaca Clinic, University Hospital, IMIB\u2010Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1lvaro","family":"Navarro\u2010Barrios","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery and Transplantation Virgen de La Arrixaca Clinic, University Hospital, IMIB\u2010Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 J.","family":"L\u00f3pez\u2010Esp\u00edn","sequence":"additional","affiliation":[{"name":"Miguel Hernandez University Elche Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio","family":"Ar\u00e9valo\u2010P\u00e9rez","sequence":"additional","affiliation":[{"name":"Radiology Department Memorial Sloan Kettering Cancer Center New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascual","family":"Parrilla","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery and Transplantation Virgen de La Arrixaca Clinic, University Hospital, IMIB\u2010Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,5,22]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2012\u20100121"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdw235"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000141198.92114.f6"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2007.09.017"},{"key":"e_1_2_4_6_1","first-page":"521","article-title":"Preoperative portal embolization to increase safety of major hepatectomy for hilar bile duct carcinoma: a preliminary report","volume":"107","author":"Makuuchi M","year":"1990","journal-title":"Surgery"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010200012000\u201000006"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6604872"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2014.12.009"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2015.12.057"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31824856f5"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000947"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2014.08.041"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010013\u20102401\u20102"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2016.10.032"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10256"},{"key":"e_1_2_4_17_1","unstructured":"BaumgartJ JungmannF BartschFet al. Two\u2010stage hepatectomy and ALPPS for advanced bilateral liver metastases: a tailored approach balancing risk and outcome.J Gastrointest Surg(2019)10.1007\/s11605\u2010019\u201004145\u2010930820795"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000002511"},{"key":"e_1_2_4_19_1","doi-asserted-by":"crossref","unstructured":"RosokBI Host\u2010BrunsellT BrudvikKW et al (2019)Characterization of early recurrences following liver resection by ALPPS and two stage hepatectomy in patients with colorectal liver\u2010metastases and small future liver remnants; a translational substudy of the LIGRO\u2010RCT. HPB (Oxford).https:\/\/doi.org\/10.1016\/j.hpb.2018.12.003","DOI":"10.1016\/j.hpb.2018.06.008"},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100033\u20101356364"},{"key":"e_1_2_4_21_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102\u201067202013000100009"},{"key":"e_1_2_4_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9547"},{"key":"e_1_2_4_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2012.03.007"},{"key":"e_1_2_4_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"e_1_2_4_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2010.10.001"},{"key":"e_1_2_4_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/92.3.205"},{"key":"e_1_2_4_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423\u2010015\u20101285\u2010z"},{"key":"e_1_2_4_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000001046"},{"key":"e_1_2_4_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2015.12.013"},{"key":"e_1_2_4_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2015.05.017"},{"key":"e_1_2_4_31_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010014\u20104291\u20104"},{"key":"e_1_2_4_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181907fd9"},{"key":"e_1_2_4_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000145964.08365.01"},{"key":"e_1_2_4_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7580"},{"key":"e_1_2_4_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9872"},{"key":"e_1_2_4_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hpb.2016.02.003"},{"key":"e_1_2_4_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000001914"},{"key":"e_1_2_4_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000002446"},{"key":"e_1_2_4_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000001450"},{"key":"e_1_2_4_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010014\u20102513\u20103"},{"key":"e_1_2_4_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2013.03.004"},{"key":"e_1_2_4_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010017\u20104181\u20106"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-019-05031-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-019-05031-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-019-05031-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-019-05031-w","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,23]],"date-time":"2023-12-23T14:32:46Z","timestamp":1703341966000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-019-05031-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,22]]},"references-count":41,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,9,15]]}},"alternative-id":["10.1007\/s00268-019-05031-w"],"URL":"https:\/\/doi.org\/10.1007\/s00268-019-05031-w","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,22]]},"assertion":[{"value":"22 May 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}