{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T22:45:09Z","timestamp":1773269109116,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,11,14]],"date-time":"2019-11-14T00:00:00Z","timestamp":1573689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2019,11,14]],"date-time":"2019-11-14T00:00:00Z","timestamp":1573689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,11,14]],"date-time":"2019-11-14T00:00:00Z","timestamp":1573689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of this case\u2013control study is to compare the surgical outcomes of laparoscopic adrenalectomy (LA) for lesions measuring \u22656\u00a0cm versus \u22645.9\u00a0cm in diameter.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty\u2010one patients with adrenal gland lesions \u22656\u00a0cm in diameter (intervention group) were identified. Patients were matched to 81 patients with adrenal gland \u22645.9\u00a0cm in diameter (control group) based on disease (Conn\u2013Cushing syndrome, pheochromocytoma, primary or secondary adrenal cancer or other disease), lesion side (right, left), surgical technique (anterior transperitoneal approach for right and left LA or anterior transperitoneal submesocolic for left LA) and body mass index class (18\u201324.9, 25\u201329.9, 30\u201334.9, 35\u201339.9, \u226540\u00a0kg\/m<jats:sup>2<\/jats:sup>). Surgical outcomes were compared between the intervention and control groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean operative time was statistically significantly longer in the interventional arm (101.4\u2009\u00b1\u200952.4 vs. and 85\u2009\u00b1\u200931.6\u00a0min, <jats:italic>p<\/jats:italic>\u2009=\u20090.0174). Eight conversions were observed in the intervention group (9.8%) compared to four in the control group (4.9%) (<jats:italic>p<\/jats:italic>\u2009=\u20090.3690). Five (6.1%) and three (3.7%) postoperative complications were observed in the intervention and control groups, respectively (<jats:italic>p<\/jats:italic>\u2009=\u20090.7196). Mean postoperative hospital stay was 4.6\u2009\u00b1\u20092.4 and 4.1\u2009\u00b1\u20092.3\u00a0days in the intervention and control groups, respectively (<jats:italic>p<\/jats:italic>\u2009=\u20090.1957).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Operative time was statistically significantly longer in adrenal gland lesions \u22656\u00a0cm in diameter (vs. \u22645.9\u00a0cm). Conversion and complication rates were also higher, but the difference was not statistically significant. Based on the present data, adrenal gland lesions \u22656\u00a0cm in diameter are not an absolute contraindication to the laparoscopic approach.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-019-05287-2","type":"journal-article","created":{"date-parts":[[2019,11,14]],"date-time":"2019-11-14T20:01:38Z","timestamp":1573761698000},"page":"810-818","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Are Adrenal Lesions of 6\u00a0cm or More in Diameter a Contraindication to Laparoscopic Adrenalectomy? 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