{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T03:19:49Z","timestamp":1785467989703,"version":"3.56.0"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T00:00:00Z","timestamp":1579564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T00:00:00Z","timestamp":1579564800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T00:00:00Z","timestamp":1579564800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Anastomotic leakage after rectal resection represents a severe complication for the patient and requires an early and appropriate management. Endoscopic vacuum therapy (EVT) has become the treatment of choice for anastomotic leakage after rectal resection in several institutions in Germany, and commercially available systems are currently distributed in approximately 30 countries worldwide. However, there is no evidence that EVT is superior to any other treatment for anastomotic leakage after rectal resection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty\u2010one patients treated with EVT for anastomotic leakage after rectal resection were retrospectively compared to a historical cohort of 41 patients that received conventional treatment. Primary endpoints were death, treatment success and long\u2010term preservation of intestinal continuity. Secondary endpoints were length of hospital stay and duration of treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was no difference in mortality (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.624). The intention\u2010to\u2010treat analysis showed a significantly higher success rate of EVT compared to conventional treatment (95.2% vs. 65.9%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.011). EVT was associated with preservation of intestinal continuity in a significant higher percentage of patients than patients undergoing conventional treatment (86.7% vs. 37.5%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). Conventional treatment tended to a shorter length of hospital stay (31.1 vs. 42.2\u00a0days,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.066) but with no difference in overall duration of treatment. Time until closing of a diverting stoma did not differ between groups (10.2\u00a0months in the EVT group vs. 9.4\u00a0months in the conventional treatment group,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.721).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>According to this retrospective study, conventional therapy and EVT are both options for the treatment of anastomotic leakage after rectal resection. EVT might be more effective in terms of definite healing and preservation of intestinal continuity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00268-019-05349-5","type":"journal-article","created":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T12:03:05Z","timestamp":1579608185000},"page":"1277-1282","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Comparison Between Endoscopic Vacuum Therapy and Conventional Treatment for Leakage After Rectal Resection"],"prefix":"10.1002","volume":"44","author":[{"given":"Florian","family":"K\u00fchn","sequence":"first","affiliation":[{"name":"Department of General, Thoracic, Vascular and Transplantation Surgery University of Rostock Schillingallee 35 18057 Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Janisch","sequence":"additional","affiliation":[{"name":"Department of General, Thoracic, Vascular and Transplantation Surgery University of Rostock Schillingallee 35 18057 Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Schwandner","sequence":"additional","affiliation":[{"name":"Department of General, Thoracic, Vascular and Transplantation Surgery University of Rostock Schillingallee 35 18057 Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Gock","sequence":"additional","affiliation":[{"name":"Department of General, Thoracic, Vascular and Transplantation Surgery University of Rostock Schillingallee 35 18057 Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Wedermann","sequence":"additional","affiliation":[{"name":"Department of General, Thoracic, Vascular and Transplantation Surgery University of Rostock Schillingallee 35 18057 Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Witte","sequence":"additional","affiliation":[{"name":"Department of General, Thoracic, Vascular and Transplantation Surgery University of Rostock Schillingallee 35 18057 Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernst","family":"Klar","sequence":"additional","affiliation":[{"name":"Department of General, Thoracic, Vascular and Transplantation Surgery University of Rostock Schillingallee 35 18057 Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leif","family":"Schiffmann","sequence":"additional","affiliation":[{"name":"Department of General, Thoracic, Vascular and Transplantation Surgery University of Rostock Schillingallee 35 18057 Rostock Germany"},{"name":"Department of General, Visceral and Thoracic Surgery Helios Klinikum Aue Gartenstra\u00dfe 6 08280 Aue Germany"},{"name":"Department of Surgery University of Rostock Schillingallee 35 18057 Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,1,21]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000637\u2010199706000\u201000002"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010007\u20109706\u2010x"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605\u2010015\u20103017\u20107"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102482\u201013\u201043"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs5.50124"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384\u2010005\u20100083\u20104"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010013\u20102340\u2010y"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12867"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2008.09.012"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463\u20101318.2007.01417.x"}],"container-title":["World 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Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-019-05349-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-019-05349-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-019-05349-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-019-05349-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T05:47:57Z","timestamp":1766468877000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-019-05349-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,21]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.1007\/s00268-019-05349-5"],"URL":"https:\/\/doi.org\/10.1007\/s00268-019-05349-5","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,21]]},"assertion":[{"value":"21 January 2020","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no competing interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interests"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"According to local ethics committee (Rostock University), no formal ethics approval was required in this retrospective study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent forms about the procedures were obtained from all patients.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}