{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T19:01:17Z","timestamp":1771959677983,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,2,13]],"date-time":"2020-02-13T00:00:00Z","timestamp":1581552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2020,2,13]],"date-time":"2020-02-13T00:00:00Z","timestamp":1581552000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,2,13]],"date-time":"2020-02-13T00:00:00Z","timestamp":1581552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There is a paucity of data on the presentation and surgical management of pheochromocytoma in developing nations, particularly in Africa.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study was a retrospective review, which included all patients managed by the Groote Schuur Hospital\/University of Cape Town Endocrine Surgery unit for pheochromocytoma and abdominal paragangliomas, from January 2002 to June 2019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty patients were included in the study, of which 33% were male and 67% female. The mean age was 47 years (range 14\u201381). The median tumor size was 6\u00a0cm, with 45% larger than 6\u00a0cm. 92% were located in the adrenal gland (87% unilateral, 5% bilateral), and 8% were extra\u2010adrenal. The conversion rate for laparoscopic cases was 20%, with 55% of cases overall completed laparoscopically. Eleven patients with tumors &gt; 6\u00a0cm were initially attempted laparoscopically, of which 3 were converted to open, without any associated increased morbidity. A major adverse event was recorded for 5 cases (8%), including 1\u00a0mortality. Overall morbidity, blood loss, operating time and hospital stay were all significantly reduced in the laparoscopic group. There were 5 patients with malignant disease (8%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This large series, from an established academic endocrine surgery unit in Africa, can serve as a benchmark for units with similar settings and resource limitations, to compare their surgical management and perioperative outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-020-05420-6","type":"journal-article","created":{"date-parts":[[2020,2,13]],"date-time":"2020-02-13T17:02:53Z","timestamp":1581613373000},"page":"1918-1924","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Surgery for Pheochromocytoma: A Single\u2010Center Review of 60 Cases from South Africa"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3265-1049","authenticated-orcid":false,"given":"D.","family":"Nel","sequence":"first","affiliation":[{"name":"Division of General Surgery Groote Schuur Hospital and University of Cape Town Cape Town South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Panieri","sequence":"additional","affiliation":[{"name":"Division of General Surgery Groote Schuur Hospital and University of Cape Town Cape Town South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Malherbe","sequence":"additional","affiliation":[{"name":"Division of General Surgery Groote Schuur Hospital and University of Cape Town Cape Town South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Steyn","sequence":"additional","affiliation":[{"name":"Division of Nuclear Medicine Groote Schuur Hospital and University of Cape Town Cape Town South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Cairncross","sequence":"additional","affiliation":[{"name":"Division of General Surgery Groote Schuur Hospital and University of Cape Town Cape Town South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,2,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2014.04.001"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/j.cpsurg.2013.12.001"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(05)67139\u20105"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014\u20101498"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE\u201016\u20100033"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010003\u20109199\u20101"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445\u20101433.2004.03024.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010007\u20109489\u20102"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2006.07.008"},{"key":"e_1_2_7_11_1","first-page":"276","article-title":"Laparoscopic compared with open adrenalectomy for resection of pheochromocytoma: a review of 47 cases","volume":"51","author":"Humphrey R","year":"2008","journal-title":"Can J Surg"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.2165\/11530430\u2010000000000\u201000000"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000164175.26785.06"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010002\u20106632\u2010x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.7196\/SAMJ.4320"},{"key":"e_1_2_7_16_1","first-page":"52","article-title":"Characteristics and outcome of patients with pheochromocytoma at a tertiary endocrinology clinic in Durban, South Africa over 14 years","volume":"23","author":"Zorgani AE","year":"2018","journal-title":"J Endocrinol Metab Diabetes S Afr"},{"key":"e_1_2_7_17_1","first-page":"71","article-title":"Phaeochromocytoma: experience with 12 cases in Tikur Anbessa, Addis Ababa, Ethiopia","volume":"9","author":"Johnson O","year":"2004","journal-title":"East Cent Afr J Surg"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.4236\/ojemd.2018.81003"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423\u2010011\u20100879\u20103"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE\u201009\u20100384"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1500681"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2010.159"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010010\u20100744\u20105"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423\u2010019\u201001768\u2010z"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2001.118373"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-020-05420-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-020-05420-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-020-05420-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-020-05420-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,23]],"date-time":"2023-12-23T15:19:17Z","timestamp":1703344757000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-020-05420-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,13]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["10.1007\/s00268-020-05420-6"],"URL":"https:\/\/doi.org\/10.1007\/s00268-020-05420-6","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,13]]},"assertion":[{"value":"13 February 2020","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standard"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}