{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T00:06:43Z","timestamp":1704672403953},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T00:00:00Z","timestamp":1589155200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T00:00:00Z","timestamp":1589155200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T00:00:00Z","timestamp":1589155200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The Pringle maneuver is often used in liver surgery to minimize bleeding during liver transection. Many authors have demonstrated that intermittent use of the Pringle maneuver is safe and effective when performed appropriately. However, some studies have reported that the Pringle maneuver is a significant risk factor for portal vein thrombosis. In this study, we evaluated the effectiveness of portal vein flow after the Pringle maneuver and the impact that massaging the hepatoduodenal ligament after the Pringle maneuver has on portal vein flow.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Patients treated with the Pringle maneuver for hepatectomies performed to treat hepatic disease at our hospital between August 2014 and March 2019 were included in the study (<jats:italic>N<\/jats:italic>\u2009=\u2009101). We divided these patients into two groups, a massage group and nonmassage group. We measured portal vein blood flow with ultrasonography before and after clamping of the hepatoduodenal ligament. We also evaluated laboratory data after the hepatectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Portal vein flow was significantly lower after the Pringle maneuver than before clamping of the hepatoduodenal ligament. The portal vein flow after the Pringle maneuver was improved following massage of the hepatoduodenal ligament. After hepatectomy, serum prothrombin time was significantly higher and serum C\u2010reactive protein was significantly lower in the massage group than in the nonmassage group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Massaging the hepatoduodenal ligament after the Pringle maneuver is recommended in order to quickly recover portal vein flow during hepatectomy and to improve coagulability.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-020-05570-7","type":"journal-article","created":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T15:04:05Z","timestamp":1589209445000},"page":"3086-3092","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Massage of the Hepatoduodenal Ligament Recovers Portal Vein Flow Immediately After the Pringle Maneuver in Hepatectomy"],"prefix":"10.1002","volume":"44","author":[{"given":"Junji","family":"Ueda","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Hepato\u2010Biliary\u2010Pancreatic Surgery Nippon Medical School 1\u20105\u20101, Bunkyo\u2010ku Sendagi 113\u20108603 Tokyo Japan"},{"name":"Department of Gastrointestinal Surgery Nippon Medical School Chiba Hokusoh Hospital 1715 Kamagari Inzai 270\u20101694 Chiba Japan"},{"name":"Department of Gastrointestinal Surgery Nippon Medical School Musashi Kosugi Hospital 1\u2010396 Kosugi Nakahara\u2010ku 211\u20108533 Kawasaki Japan"},{"name":"Department of Surgery Nippon Medical School Tamanagayama Hospital 1\u20107\u20101, Nagayama 206\u20108512 Tama\u2010City Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Mamada","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Hepato\u2010Biliary\u2010Pancreatic Surgery Nippon Medical School 1\u20105\u20101, Bunkyo\u2010ku Sendagi 113\u20108603 Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhiko","family":"Taniai","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Nippon Medical School Musashi Kosugi Hospital 1\u2010396 Kosugi Nakahara\u2010ku 211\u20108533 Kawasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masato","family":"Yoshioka","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Hepato\u2010Biliary\u2010Pancreatic Surgery Nippon Medical School 1\u20105\u20101, Bunkyo\u2010ku Sendagi 113\u20108603 Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Hirakata","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Nippon Medical School Chiba Hokusoh Hospital 1715 Kamagari Inzai 270\u20101694 Chiba 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