{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T14:50:55Z","timestamp":1788187855410,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,5,23]],"date-time":"2020-05-23T00:00:00Z","timestamp":1590192000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2020,5,23]],"date-time":"2020-05-23T00:00:00Z","timestamp":1590192000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,5,23]],"date-time":"2020-05-23T00:00:00Z","timestamp":1590192000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Potassium iodide (KI) treatment affects the vascularity of the thyroid gland and therefore may improve intraoperative visualization of essential structures. However, clear evidence for its usage is lacking, and its implementation in patients suffering from Graves' disease is becoming rare. The objective of this retrospective study was to assess the impact of KI treatment on the intraoperative course and the outcome of patients undergoing thyroidectomy for Graves' diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study included 442 patients: 125 patients (28.3%) who received a preoperative treatment with KI (\u201cGroup KI\u201d) and 317 patients (71.7%) without a KI therapy (\u201cGroup No\u2010KI\u201d). Indication for KI treatment was a thyroid bruit (82.5%), as well as hyperthyroidism refractive to medical treatment with antithyroid drugs (17.4%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All patients underwent total thyroidectomy. Permanent vocal cord paresis and permanent hypoparathyroidism were similar in both groups. KI treatment was associated with a significantly longer operative time (142 vs. 128\u00a0min, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and a significant higher weight of the thyroid gland. KI treatment did not impact duration of hospital stay or occurrence of secondary hemorrhage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The complication rate of this study population with clinically severe GD was very low\u2014which may be caused by pre\u2010treatment of patients. The complementary option of a potassium iodide treatment before surgery remains a possibility and should be implemented individually.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-020-05593-0","type":"journal-article","created":{"date-parts":[[2020,5,23]],"date-time":"2020-05-23T20:02:19Z","timestamp":1590264139000},"page":"3405-3409","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Preoperative Potassium Iodide Treatment in Patients Undergoing Thyroidectomy for Graves' Disease\u2014Perspective of a European High\u2010Volume Center"],"prefix":"10.1002","volume":"44","author":[{"given":"Kirsten","family":"Lindner","sequence":"first","affiliation":[{"name":"Department of Surgery University Medical Center Schleswig\u2010Holstein, Campus Luebeck Ratzeburger Allee 160 23538 Luebeck 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