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We evaluated the impact of race on presentation, preoperative evaluation, and surgical outcomes for patients undergoing parathyroidectomy for primary hyperparathyroidism (PHPT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective cohort study of patients undergoing parathyroidectomy for PHPT at a single center (1997\u20132015). Patients were classified by self\u2010identified race, as African\u2010American or White. The primary outcome was disease severity at referral. The secondary outcome was completeness of preoperative evaluation. Operative success and surgical cure were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 2392 patients were included. The majority of patients (87.6%) were White. African\u2010American patients had higher rates of comorbid disease as well as higher preoperative calcium (10.9 vs.10.8\u00a0mg\/dl, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and PTH levels (122 vs. 97 pg\/ml, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). White patients were more likely to have history of bone loss documented by DXA and nephrolithiasis. African\u2010American patients had lower rates of complete preoperative evaluation including DXA scan. Operatively, African\u2010American patients had larger glands by size (1.7 vs. 1.5\u00a0cm, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and mass (573 vs. 364\u00a0mg, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). We observed similar operative success (98.9 vs. 98.0%, <jats:italic>p<\/jats:italic>\u2009=\u20090.355) and cure rates (98.3 vs. 97.0%, <jats:italic>p<\/jats:italic>\u2009=\u20090.756).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>At the time of surgical referral, African\u2010American patients with PHPT have more biochemically severe disease and higher rates of incomplete evaluation. Operative success and cure rates are comparable.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-020-05791-w","type":"journal-article","created":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T19:02:35Z","timestamp":1601060555000},"page":"180-187","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Racial Disparities in Primary Hyperparathyroidism"],"prefix":"10.1002","volume":"45","author":[{"given":"Jennifer","family":"Fieber","sequence":"first","affiliation":[{"name":"Department of Surgery Hospital of the University of Pennsylvania 3400 Spruce Street 4 Silverstein Pavilion 19104 Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5967-7433","authenticated-orcid":false,"given":"Kristin","family":"Goodsell","sequence":"additional","affiliation":[{"name":"Perelman School of Medicine University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel R.","family":"Kelz","sequence":"additional","affiliation":[{"name":"Department of Surgery Hospital of the University of Pennsylvania 3400 Spruce Street 4 Silverstein Pavilion 19104 Philadelphia PA USA"},{"name":"Perelman School of Medicine University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae P.","family":"Ermer","sequence":"additional","affiliation":[{"name":"Department of Surgery Hospital of the University of Pennsylvania 3400 Spruce Street 4 Silverstein Pavilion 19104 Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Wirtalla","sequence":"additional","affiliation":[{"name":"Department of Surgery Hospital of the University of Pennsylvania 3400 Spruce Street 4 Silverstein Pavilion 19104 Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas L.","family":"Fraker","sequence":"additional","affiliation":[{"name":"Department of Surgery Hospital of the University of Pennsylvania 3400 Spruce Street 4 Silverstein Pavilion 19104 Philadelphia PA USA"},{"name":"Perelman School of Medicine University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Wachtel","sequence":"additional","affiliation":[{"name":"Department of Surgery Hospital of the University of Pennsylvania 3400 Spruce Street 4 Silverstein Pavilion 19104 Philadelphia PA USA"},{"name":"Perelman School of Medicine University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012\u20104022"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(17)31430\u20107"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199910213411701"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007\u20101215"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2006.07.032"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2016.06.062"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.31076"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000534"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.31029"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2018.05.011"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000001078"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2010.141"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2016.11.019"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012\u20102043"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31812eecc4"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010014\u20103610\u20100"},{"key":"e_1_2_7_18_1","unstructured":"Revisions to the Standards for the Classification of Federal Data on Race and Ethnicity Office of Management and Budget 30 October 1997"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650\u2010199801000\u201000004"},{"key":"e_1_2_7_20_1","unstructured":"Michigan Population Studies Center Institute for Social Research Zip Code Characteristics:Mean and Median Household Income. 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